ArticleThoracic cancer2019
Feasibility of nodal classification for non-small cell lung cancer by merging current N categories with the number of involved lymph node stations.
Article in Thoracic cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- N1 Staging in Non-Small Cell Lung Cancer: Current Situation, Limitations, and the Importance of Peripheral Nodal Assessment.Cancers · 2026Review
- Number of involved nodal stations predicts survival in small cell lung cancer.BMC pulmonary medicine · 2024Article
- The additional radiotherapy to adjuvant chemotherapy improves the prognosis of stage III-N2 with highest mediastinal lymph node metastasis in non-small cell lung cancer.Journal of cancer research and clinical oncology · 2023Article
- Number of involved nodal stations: a better lymph node classification for clinical stage IA lung adenocarcinoma.Journal of the National Cancer Center · 2023Article
- Portrayal of video-assisted mediastinoscopic lymphadenectomy's range subsequent to its simultaneous use with uniportal VAT-lobectomy for left-sided NSCLC: a case-based perspective.Journal of cardiothoracic surgery · 2023Article
- Locally advanced non-small cell lung cancer: current issues and recent trends.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023Review
- [Review for N2 Sub-staging in Non-small Cell Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2022Article
- A Comprehensive Comparison of Different Nodal Subclassification Methods in Surgically Resected Non-Small-Cell Lung Cancer Patients.Annals of surgical oncology · 2022Review
- Effect of 3A lymph node resection on survival in patients with right-sided NSCLC: a retrospective, multicentre, propensity-score matching study.Journal of thoracic disease · 2022Article
- A new N descriptor for non-small cell lung cancer: the classification based on anatomic location, number and ratio of metastatic lymph nodes.Translational lung cancer research · 2022Article
- Prognostic impact of extranodal extension in patients with pN1-N2 lung adenocarcinoma.Journal of cancer research and clinical oncology · 2021Article
- Surgical mediastinal lymph node staging for non-small-cell lung carcinoma.Translational lung cancer research · 2021Article
- Prognostic impact of the number of involved lymph node stations in patients with completely resected non-small cell lung cancer: a proposal for future revisions of the N classification.General thoracic and cardiovascular surgery · 2020Article
- Alternative methods of lymph node staging in lung cancer: a narrative review.Journal of thoracic disease · 2020Review
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this study was to assess the prognoses of patients with non-small cell lung cancer (NSCLC) according to the current nodal (N) categories of the tumor, node and metastasis (TNM) classification and the number of involved lymph node stations.
methodsFive hundred and seventy patients with NSCLC underwent surgery from 1 January 2005 to 31 December 2009 and were analysed retrospectively. Postoperative overall survival was analysed according to two nodal classifications: the current N0, N1, N2 and N3 categories and those based on the number of involved nodal stations: N0, N1a (single N1), N1b (multiple N1), N2a1 (single N2 without N1), N2a2 (single N2 with N1), N2b1 (multiple N2 without N1) and N2b2 (multiple N2 with N1).
resultsFive-year survival rates were 76.1%, 53.4% and 26.3% for N0, N1 and N2, respectively (P < 0.001). When survival was analysed by the number of involved nodal stations, the groups with significant differences were maintained; otherwise, they were merged, and new codes were assigned as follows for exploratory analyses: NA (N0), NB (N1a), NC (N1b, N2a (i.e., N2a1 and N2a2) and N2b1) and ND (N2b2). Five-year survival rates were 76.1%, 60.0%, 39.1%, and 11.4% for NA, NB, NC and ND, respectively, and there were significant differences among them. This N classification was an independent prognostic factor in multivariate analyses.
conclusionPending prospective and international validation, it is practical to merge the current N categories with the number of involved lymph node stations when evaluating the postoperative prognosis of NSCLC patients.
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