Evidence map›Paper›PMID 31207094›Full record

ArticleInternational wound journal2019

Cold atmospheric plasma promotes different types of superficial skin erosion wounds healing.

Jing Gao, Liyun Wang, Chuankai Xia, Xingyu Yang, Zhicheng Cao, Lei Zheng, Randy Ko, Changbing Shen, Chunjun Yang, Cheng Cheng

2 registry-linked trialsAbstract read
In one paragraph

Article in International wound journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04886323 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Cold Atmospheric Plasma on Malassezia Folliculitis: a Randomized Controlled Trial

TypeinterventionalSponsorThe Second Hospital of Anhui Medical UniversityRan2022 to 2023Enrolled50ConditionsMalassezia FolliculitisArmsCold atmospheric plasma treatment device, Itraconazole Capsules
NCT06543316 narecruitingnot on this mapstarted 2025, after this paper: background citation

Accelerated Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment

TypeinterventionalSponsorChristopher C. Thompson, MD, MScRan2025 to 2028Enrolled100ConditionsRoux-en-y Anastomosis Site, Marginal Ulcer, Marginal Ulcer (Peptic) or Erosion, UlcerArmsLow Thermal Plasma (LTP) Treatment, Standard of Care Ulcer Treatment (typically PPI Administration)
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Comparing the efficacy of plasma exeresis and cryotherapy for the treatment of seborrheic keratosis: A randomized controlled trial.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jing GaoDepartment of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei, China.
Liyun WangDepartment of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei, China.
Chuankai XiaDepartment of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei, China.
Xingyu YangDepartment of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei, China.
Zhicheng CaoDepartment of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei, China.
Lei ZhengDepartment of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei, China.
Randy KoDepartment of Dermatology, University of New Mexico School of Medicine, Albuquerque, New Mexico.
Changbing ShenDepartment of Dermatology, China-Japan Friendship Hospital, Beijing, China.
Chunjun YangDepartment of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei, China.
Cheng ChengApplied Plasma Division, Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, China.

Funding

Anhui Medical University Scientific Research 2018xkj040Spark plan project of the Second Affiliated Hospital of Anhui Medical University 2015hhjh04
6 · The paper itself

Abstract

Superficial skin erosion wounds are very common in the clinic, and conventional treatments are not always effective; thus, effective and novel therapy is needed. Cold atmospheric plasma (CAP) has been recognised as a promising approach to wound healing. The purpose of this study is to show the potential clinical application of CAP for the healing of different kinds of superficial skin wounds. Seven patients with different kinds of superficial skin wounds (two patients with pyoderma gangrenosum, two patients with trauma would, one patient with giant genital wart, one patient with diabetic foot, and one patient with chronic eczema) were recruited to this study. All patients accepted and received CAP treatment every other day till the wound healed. The expected results were complete wound healing after CAP treatment. All patients achieved complete wound healing after several rounds (range from two to eight) of CAP treatment, and there was no side effect observed. CAP may provide a new and effective choice to solve the problem of the healing of superficial wounds that are not only caused by trauma but also because of eczema. CAP has certain value in the treatment of superficial skin diseases in the future.

Indexed as

AdultAgedDiabetic FootFemaleHumansMaleMiddle AgedPlasma GasesPrognosisRetrospective StudiesSampling StudiesSeverity of Illness IndexSkin UlcerTreatment OutcomeWound HealingWounds and InjuriesPlasma Gasescold atmospheric plasmaskin lesiontraumatic wound

Identifiers

PMID31207094
PMCPMC7949367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.