ArticleJournal of applied clinical medical physics2019
Characterizing mechanical and medical imaging properties of polyvinyl chloride-based tissue-mimicking materials.
Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026Review
- Bake your phantom-low-cost recipes for dough-based, tissue-mimicking CT phantoms.European radiology · 2026Article
- Low-Cost Photoacoustic Imaging System for Vascular Occlusion Detection in Polymer Phantoms.Journal of lasers in medical sciences · 2026Article
- Evaluation of physical properties and image quality of a breast tissue phantom with glycerol-enhanced polyvinyl chloride plastisol for ultrasound imaging.Ultrasonography (Seoul, Korea) · 2025Article
- Silicone phantoms fabricated with multi-material extrusion 3D printing technology mimicking imaging properties of soft tissues in CT.Zeitschrift fur medizinische Physik · 2025Article
- Evaluation of physical properties and image of polyvinyl chloride as breast tissue equivalence for dual-modality (mammography and ultrasound).Physical and engineering sciences in medicine · 2023Article
- Patient-Specific 3D-Printed Low-Cost Models in Medical Education and Clinical Practice.Micromachines · 2023Review
- Three-dimensional opto-thermo-mechanical model for predicting photo-thermal optical coherence tomography responses in multilayer geometries.Biomedical optics express · 2022Article
- Mechanical and medical imaging properties of 3D-printed materials as tissue equivalent materials.Journal of applied clinical medical physics · 2022Article
- Development of patient-specific 3D-printed breast phantom using silicone and peanut oils for magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Polyvinyl chloride (PVC) is a commonly used tissue-mimicking material (TMM) for phantom construction using 3D printing technology. PVC-based TMMs consist of a mixture of PVC powder and dioctyl terephthalate as a softener. In order to allow the clinical use of a PVC-based phantom use across CT and magnetic resonance imaging (MRI) imaging platforms, we evaluated the mechanical and physical imaging characteristics of ten PVC samples. The samples were made with different PVC-softener ratios to optimize phantom bioequivalence with physiologic human tissue. Phantom imaging characteristics, including computed tomography (CT) number, MRI relaxation time, and mechanical properties (e.g., Poisson's ratio and elastic modulus) were quantified. CT number varied over a range of approximately -10 to 110 HU. The relaxation times of the T1-weighted and T2-weighted images were 206.81 ± 17.50 and 20.22 ± 5.74 ms, respectively. Tensile testing was performed to evaluate mechanical properties on the three PVC samples that were closest to human tissue. The elastic moduli for these samples ranged 7.000-12.376 MPa, and Poisson's ratios were 0.604-0.644. After physical and imaging characterization of the various PVC-based phantoms, we successfully produced a bioequivalent phantom compatible with multimodal imaging platforms for machine calibration and image optimization/benchmarking. By combining PVC with 3D printing technologies, it is possible to construct imaging phantoms simulating human anatomies with tissue equivalency.
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