Evidence map›Paper›PMID 31206768›Full record

Trial reportJournal of clinical laboratory analysis2019

Effects of dual plasma molecular adsorption system on liver function, electrolytes, inflammation, and immunity in patients with chronic severe hepatitis.

Gao Chen, Mengzheng Wu, Bibo Wu, Feifei Liu, Jianying Liu, Li Liu

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. [Clinical application and technical operation specification of dual plasma molecular adsorption system].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
  7. Article
  8. [Analysis of the prognosis and survival of patients with acute-on-chronic liver failure].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gao ChenDepartment of Infection, Deyang People's Hospital, Deyang, China.ORCID https://orcid.org/0000-0002-9768-3877
Mengzheng WuDepartment of Infection, Deyang People's Hospital, Deyang, China.
Bibo WuDepartment of Infection, Deyang People's Hospital, Deyang, China.
Feifei LiuDepartment of Infection, Deyang People's Hospital, Deyang, China.
Jianying LiuDepartment of Infection, Deyang People's Hospital, Deyang, China.
Li LiuDepartment of Infection, Deyang People's Hospital, Deyang, China.
Deyang Stomatological Hospital · CN

Funding

Scientific Research Foundation Project of Deyang Science and Technology Bureau of Sichuan Province 2018SZS092
6 · The paper itself

Abstract

backgroundTo investigate the effects of dual plasma molecular adsorption system (DPMAS) on the liver function, electrolytes, inflammation, and immunity in patients with chronic severe hepatitis (CSH).

methodsTotal of 162 patients with CSH treated in our hospital from March 2016 to December 2018 were enrolled and equally randomly divided into control group (n = 81) and observation group (n = 81). The patients in control group were treated with plasma exchange, while those in observation group were additionally treated with DPMAS based on the treatment in control group. The liver function, electrolytes, inflammation, and immunity were evaluated and compared between the two groups.

resultsAfter treatment, the liver function indexes in observation group were significantly favorable compared with those in control group, with the reduction in TBIL, DBIL, ALT, and rise of CHE levels (P < 0.05). The levels of K

conclusionDual plasma molecular adsorption system can effectively improve the liver function, effectively correct the electrolyte disorders, reduce the inflammatory response, and adjust the immunity in patients with CSH.

Indexed as

ImmunityAdsorptionAdultAgedElectrolytesFemaleHepatitis, ChronicHumansInflammationLiverMaleMiddle AgedPlasmaElectrolyteschronic severe hepatitisdual plasma molecular adsorption systemelectrolytesimmune functionliver function

Identifiers

PMID31206768
PMCPMC6757123
OpenAlexW2951156313

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.