ArticleCancer2019
Does race predict survival for women with invasive breast cancer?
Article in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Racial Differences in Breast Cancer Survival Between Black and White Women According to Tumor Subtype: A Systematic Review and Meta-Analysis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Pooled it
- Assessing racial disparities in disease outcomes of patients with high-risk, triple-negative breast cancer and residual disease after neoadjuvant therapy: a post-hoc analysis of the ECOG-ACRIN 1131 clinical trial.Breast cancer research and treatment · 2025Trial
- Impact of Socioeconomic Factors on Surgical Approach and Outcomes in Young Women with Breast Cancer.European journal of breast health · 2025Article
- Disparities in the Surgical Management of the Axilla by Self-Identified Race in the Multicenter Neoadjuvant I-SPY2 Trial.Annals of surgical oncology · 2025Article
- First mammogram-detected cancers portend worse survival in young women diagnosed with breast cancer.Breast cancer research and treatment · 2025Article
- Article
- West African Genetic Ancestry and Breast Cancer Outcomes Among Black Women.JAMA network open · 2024Observational
- A nomogram and risk stratification system for predicting survival in T1-2N0-1 breast cancer patients with liver metastasis in females: a population-based study.Biomedical engineering online · 2024Article
- A nomogram for predicting overall survival of breast cancer with regional lymph node metastasis in young women.Translational cancer research · 2024Article
- Racial/ethnic differences in the clinical presentation and survival of breast cancer by subtype.Frontiers in oncology · 2024Article
- Survival of Filipino women with breast cancer in the United States.Cancer medicine · 2023Article
- Breast cancer treatment receipt and the role of financial stress, health literacy, and numeracy among diverse breast cancer survivors.Breast cancer research and treatment · 2023Article
- The impact of race and age on response to neoadjuvant therapy and long-term outcomes in Black and White women with early-stage breast cancer.Breast cancer research and treatment · 2023Article
- The Cancer Genomic Integration Model for Symptom Science (CGIMSS): A Biopsychosocial Framework.Biological research for nursing · 2023Review
- The Impact of Race and Age on Response to Neoadjuvant Therapy and Long-Term Outcomes in Black and White Women with Early-Stage Breast Cancer.Research square · 2023Article
- Concomitant analyses of intratumoral microbiota and genomic features reveal distinct racial differences in breast cancer.NPJ breast cancer · 2023Article
- The disparities in prognostic prediction and annualized hazard function in different molecular subtypes between young Chinese and White American women with breast cancer.Frontiers in oncology · 2023Article
- NURR1 Is Differentially Expressed in Breast Cancer According to Patient Racial Identity and Tumor Subtype.BioMedInformatics · 2022Article
- Machine learning models for predicting survival in patients with ampullary adenocarcinoma.Asia-Pacific journal of oncology nursing · 2022Article
- Development and validation of nomograms for predicting survival in patients with de novo metastatic triple-negative breast cancer.Scientific reports · 2022Article
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Funding
Abstract
backgroundBlack women with breast cancer have lower survival rates and higher recurrence rates in comparison with white women. This study compared treatment and survival outcomes for black and white women at a highly specialized tertiary care cancer center.
methodsAn institutional review board-approved, retrospective institutional database review was performed to identify all black women treated for invasive breast cancer between 2005 and 2010. Women with a prior history of breast cancer, stage IV cancer, or bilateral breast cancer were excluded. White women had similar exclusion criteria applied and were then matched to black women 1:1 by age and diagnosis year. Clinicopathologic and treatment variables were compared by race. Kaplan-Meier methodology was used to estimate overall survival (OS) and disease-free survival (DFS); a multivariable analysis was conducted with Cox regression models.
resultsThe study group consisted of 1332 women (666 black). The median tumor size was larger in black women (1.6 vs 1.3 cm; P < .001). Black women had more nodal disease (41.1% vs 32%; P < .001) and had tumors that were more frequently an estrogen receptor-negative (32.9% vs 15%; P < .001), progesterone receptor-negative (47.1% vs 30.2%; P < .001), or triple-negative (TN) subtype (24% vs 8.9%; P < .001) in comparison with white women. Black women also had inferior DFS and OS; race was not an independent prognostic indicator in the multivariable analysis.
conclusionsBlack women had more advanced disease and adverse prognostic indicators at diagnosis, but race was not an independent predictor of outcome. Black women were significantly more likely to have TN breast cancer. Further research is necessary to understand the differences in tumor biology associated with race.
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