Evidence map›Paper›PMID 31206174›Full record

ArticleClinical and experimental immunology2019

Decreased A20 expression on circulating CD56

M Yang, Y Zhou, L Liu, S Wang, J Jiang, Q Shang, H Yu, X Xiang, X Pang, T Li and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Innate Lymphocytes in Inflammatory Arthritis.Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

M YangDepartment of Radiology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, China.
Y ZhouDepartment of Clinical Laboratory, Binzhou Medical University Hospital, Binzhou, China.
L LiuCenter of Translational Medicine, Zibo Central Hospital Affiliated to Shandong University, Zibo, China.
S WangDepartment of Rheumatology, Zibo Central Hospital Affiliated to Shandong University, Zibo, China.
J JiangDepartment of Radiology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, China.
Q ShangCenter of Translational Medicine, Zibo Central Hospital Affiliated to Shandong University, Zibo, China.
H YuCenter of Translational Medicine, Zibo Central Hospital Affiliated to Shandong University, Zibo, China.
X XiangCenter of Translational Medicine, Zibo Central Hospital Affiliated to Shandong University, Zibo, China.
X PangCenter of Translational Medicine, Zibo Central Hospital Affiliated to Shandong University, Zibo, China.
T LiDepartment of Clinical Laboratory, Binzhou Medical University Hospital, Binzhou, China.
P ZhaoCenter of Translational Medicine, Zibo Central Hospital Affiliated to Shandong University, Zibo, China.ORCID 0000-0002-9311-1927
Shandong University · CNBinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A20, a pivotal anti-inflammatory protein, preserves immune homeostasis and regulates prolonged inflammation. A previous study has shown that A20 expression levels are down-regulated in peripheral blood mononuclear cells (PBMCs) from patients with ankylosing spondylitis (AS). However, the precise role of A20 in reducing autoimmune disorders needs to be further elucidated. In this study, A20 expression was found to be preferentially reduced on circulating CD56

Indexed as

Case-Control StudiesCD56 AntigenCytokinesHumansInflammationInterferon-gammaIonomycinKiller Cells, NaturalLeukocytes, MononuclearLymphocyte ActivationSpondylitis, AnkylosingTetradecanoylphorbol AcetateTumor Necrosis Factor alpha-Induced Protein 3CD56 AntigenCytokinesInterferon-gammaIonomycinNCAM1 protein, humanTetradecanoylphorbol AcetateTNFAIP3 protein, humanTumor Necrosis Factor alpha-Induced Protein 3A20ankylosing spondylitisCD56bright NK cellsdisease activityIFN-γTNF-α

Identifiers

PMID31206174
PMCPMC6718289
OpenAlexW2952151579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.