Evidence map›Paper›PMID 31205958›Full record

ArticleJournal of immunology research2019

Circulating CD3

Ryutaro Oba, Motomichi Isomura, Akira Igarashi, Kinya Nagata

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Review
  5. Article
  6. Article
  7. From pathogenesis to therapy: extracellular vesicles in osteoarthritis.Frontiers in bioengineering and biotechnology · 2026
    Review
  8. Article
  9. Circulating Extracellular Vesicles in Cardiovascular Disease.International journal of molecular sciences · 2025
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryutaro ObaDivision of Advanced Technology and Development, BML Inc., Saitama, Japan.ORCID 0000-0003-4666-2379
Motomichi IsomuraDivision of Advanced Technology and Development, BML Inc., Saitama, Japan.
Akira IgarashiDivision of Advanced Technology and Development, BML Inc., Saitama, Japan.
Kinya NagataDivision of Advanced Technology and Development, BML Inc., Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are known to contain unique proteins that reflect the cells of origins. Activated T cells are reported to secrete various EVs. To establish T cell subset-specific biomarkers, we performed proteomic analysis with Th1- and Th2-derived EVs and identified HLA-DR as a Th1-dominated EV membrane protein. We designed a measurement system for CD3

Indexed as

Arthritis, RheumatoidBiomarkersCells, CulturedDermatitis, AtopicEpstein-Barr Virus InfectionsExtracellular VesiclesFlow CytometryHerpesvirus 4, HumanHLA-DR AntigensHumansImmunity, CellularImmunophenotypingLymphocyte ActivationOsteoarthritisProteomicsTh1 CellsBiomarkersHLA-DR Antigens

Identifiers

PMID31205958
PMCPMC6530242
OpenAlexW2944711745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.