Evidence map›Paper›PMID 31205784›Full record

ArticleJournal of ophthalmology2019

The Efficacy of Intravitreal Conbercept for Chronic Central Serous Chorioretinopathy.

Jianbo Mao, Caiyun Zhang, Chenyi Liu, Lijun Shen, Jimeng Lao, Yirun Shao, Yiqi Chen, Jiwei Tao

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jianbo MaoEye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Caiyun ZhangEye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Chenyi LiuChicago College of Optometry, Midwestern University, Downers Grove, IL, USA.
Lijun ShenEye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID 0000-0002-7518-2932
Jimeng LaoEye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yirun ShaoEye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yiqi ChenEye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jiwei TaoEye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the efficacy and safety of conbercept for patients with chronic central serous chorioretinopathy (CSC).

methodsA retrospective clinical study. Thirty-one patients (35 eyes) with chronic CSC were given intravitreal injections of conbercept and followed up for at least 6 months. Observed indicators included best-corrected visual acuity (BCVA), central macular thickness (CMT), and resolution of subretinal fluid (SRF). Serial changes in BCVA and CMT were analyzed by using repeated measures analysis of variance.

resultsDuring the 6-month follow-up, the mean number of injections required and performed was 1.77 ± 0.60. The logMAR BCVA was 0.48 ± 0.26 at the baseline, 0.34 ± 0.26, 0.30 ± 0.26, 0.27 ± 0.26, 0.24 ± 0.26, and 0.23 ± 0.26 at 2-week and 1-, 2-, 3-, and 6-month follow-ups, respectively (

conclusionsIntravitreal injection of conbercept may effectively reduce the CMT and improve the BCVA in chronic CSC in a short term of 6 months.

Identifiers

PMID31205784
PMCPMC6530212

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.