Evidence map›Paper›PMID 31205698›Full record

ArticleSAGE open medicine2019

Identifying causes of persistent HIV viremia in adult patients at an academic medical center.

Julie Steinbrink, Hannah Imlay, Krishna Rao, James Riddell

Open access · goldAbstract read
In one paragraph

Article in SAGE open medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Julie SteinbrinkDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID https://orcid.org/0000-0003-0771-3647
Hannah ImlayDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Krishna RaoDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID https://orcid.org/0000-0002-9213-7850
James RiddellDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
NCATS NIH HHS UL1 TR000433NIA NIH HHS P30 AG024824
6 · The paper itself

Abstract

objectivesDespite many advances in medicine, not all individuals with HIV are able to achieve complete virologic suppression. This retrospective study identifies variables associated with persistent HIV viremia in an academic clinic.

methodsWe studied 66 HIV-infected patients with a viral load of >200 copies/mL over 1 year, with controls matched 1:1 via a propensity score utilizing age at diagnosis, era of diagnosis, gender, and initial CD4 count. We collected data on multiple variables including medications, adherence, comorbidities, hospitalizations, and insurance status. Conditional logistic regression was used for unadjusted and adjusted analyses.

resultsA total of 66 viremic cases/matched controls were included. Fewer viremic patients were on antiretroviral therapy for all 12 months (45% vs 77%; odds ratio: 0.33,

conclusionPsychiatric illness is an important contributor to the presence of persistent viremia in HIV-infected patients and deserves further study.

Indexed as

antiretroviral therapyHIVpsychiatric illnessviremia

Identifiers

PMID31205698
PMCPMC6537052
OpenAlexW2946162320

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.