ArticleeLife2019
Rapid and iterative genome editing in the malaria parasite
Open access · goldAbstract read
In one paragraph
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 95 citations in OpenAlex.
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- Digital PCR Reveals High PvDBP1 but not PvEBP/DBP2 and PvRBP2b Copy Number in Plasmodium vivax From Duffy-Negative Individuals in Central Africa.The Journal of infectious diseases · 2026Article
- Generation of a TransgenicVaccines · 2025Article
- A novel micronemal protein MP38 is involved in the invasion of merozoites into erythrocytes.mBio · 2025Article
- DNA replication dynamics are associated with genome composition in Plasmodium species.Nucleic acids research · 2025Article
- Supersaturation mutagenesis reveals adaptive rewiring of essential genes among malaria parasites.Science (New York, N.Y.) · 2025Article
- The essential genome ofScience (New York, N.Y.) · 2025Article
- A scalable CRISPR-Cas9 gene editing system facilitates CRISPR screens in the malaria parasite Plasmodium berghei.Nucleic acids research · 2025Article
- Genome sequencing of Plasmodium malariae identifies continental segregation and mutations associated with reduced pyrimethamine susceptibility.Nature communications · 2024Article
- Genomic analysis of global Plasmodium vivax populations reveals insights into the evolution of drug resistance.Nature communications · 2024Article
- Red blood cell signaling is functionally conserved iniScience · 2024Article
- Overview ofComparative medicine · 2024Review
- Vaccines and monoclonal antibodies: new tools for malaria control.Clinical microbiology reviews · 2024Review
- Article
- The dCas9-based genome editing inmSphere · 2024Article
- Progeny counter mechanism in malaria parasites is linked to extracellular resources.PLoS pathogens · 2023Article
- Review
- The structure of a Plasmodium vivax Tryptophan Rich Antigen domain suggests a lipid binding function for a pan-Plasmodium multi-gene family.Nature communications · 2023Article
- Transfection Models to InvestigatePathogens (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 1 country.
Franziska MohringFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID 0000-0003-4726-6693
Melissa Natalie HartFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Thomas A RawlinsonThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Ryan HenriciFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
James A CharlestonFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Ernest Diez BenaventeFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Avnish PatelFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Joanna HallDivision of Infectious Disease Diagnostics, National Institute for Biological Standards and Control, Health Protection Agency, Hertfordshire, United Kingdom.
Neil AlmondDivision of Infectious Disease Diagnostics, National Institute for Biological Standards and Control, Health Protection Agency, Hertfordshire, United Kingdom.
Susana CampinoFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Taane G ClarkFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID 0000-0001-8985-9265
Colin J SutherlandFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID 0000-0003-1592-6407
David A BakerFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Simon J DraperThe Jenner Institute, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-9415-1357
Robert William MoonFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID 0000-0002-9070-4292
London School of Hygiene & Tropical Medicine · GBNational Institute for Biological Standards and Control · GBUniversity of Oxford · GB
Funding
PATHOGENESIS OF LIVER CANCER INDUCED BY CHEMICALSR01CA021157 · NCI · UNIVERSITY OF TORONTO · PI FARBER, EMMANUEL · 1985 to 1985
–Biotechnology and Biological Sciences Research Council BB/R013063/1Biotechnology and Biological Sciences Research Council London Interdiscpinary Doctoral Programme StudentshipLister Institute of Preventive Medicine Research Prize FellowMarshall Aid Commemoration Commission Marshall ScholarshipMedical Research Council MRC Career Development Award MR/M021157/1)Medical Research Council MR/M01360X/1Medical Research Council MR/M021157/1Medical Research Council MR/N010469/1Medical Research Council MR/R020973/1Medical Research Council MR/R025576/1University of London Bloomsbury Colleges Research StudentshipWellcome TrustWellcome Trust Research Training Fellowship, 108734/Z/15/ZWellcome Trust Senior Investigator Award, 106240/Z/14/ZWellcome Trust Wellcome Trust Senior Fellowship, 106917/Z/15/Z
Abstract
Tackling relapsing
Indexed as
AnimalsAntigens, ProtozoanBiomedical ResearchGene EditingHumansMalariaMalaria VaccinesMalaria, VivaxParasitesPlasmodium knowlesiProtozoan ProteinsReceptors, Cell SurfaceAntigens, ProtozoanDuffy antigen binding protein, PlasmodiumMalaria VaccinesProtozoan ProteinsReceptors, Cell SurfaceCRISPR-Cas9Duffy binding proteingeneticsgenome-editinggenomicsinfectious diseasemicrobiologyP. falciparumPlasmodium knowlesiPlasmodium vivaxvaccine
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.