ArticleAstrobiology2019
Nucleic Acid Extraction and Sequencing from Low-Biomass Synthetic Mars Analog Soils for
Article in Astrobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Using Carrier DNA in Ultra-Low Input Library Preparations for Next-Generation Sequencing.Journal of biomolecular techniques : JBT · 2026Article
- Exploring Life Detection on Mars: Understanding Challenges in DNA Amplification in Martian Regolith Analogue After Fe Ion Irradiation.Life (Basel, Switzerland) · 2025Article
- Utilizing Martian samples for future planetary exploration-Characterizing hazards and resources.Proceedings of the National Academy of Sciences of the United States of America · 2025Review
- A Comparison of Different Protocols for the Extraction of Microbial DNA Inhabiting Synthetic Mars Simulant Soil.Microorganisms · 2024Article
- Dancing the Nanopore limbo - Nanopore metagenomics from small DNA quantities for bacterial genome reconstruction.BMC genomics · 2023Article
- Analysis of Microbiomes from Ultra-Low Biomass Surfaces Using Novel Surface Sampling and Nanopore Sequencing.Journal of biomolecular techniques : JBT · 2023Article
- Development of Sensitive Methods for the Detection of Minimum Concentrations of DNA on Martian Soil Simulants.Life (Basel, Switzerland) · 2023Article
- Article
- Investigation of fungal biomolecules after Low Earth Orbit exposure: a testbed for the next Moon missions.Environmental microbiology · 2022Article
- In search of the RNA world on Mars.Geobiology · 2021Article
- CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing.BMC bioinformatics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies regarding the origins of life and Mars-Earth meteorite transfer simulations suggest that biological informational polymers, such as nucleic acids (DNA and RNA), have the potential to provide unambiguous evidence of life on Mars. To this end, we are developing a metagenomics-based life-detection instrument which integrates nucleic acid extraction and nanopore sequencing: the Search for Extra-Terrestrial Genomes (SETG). Our goal is to isolate and sequence nucleic acids from extant or preserved life on Mars in order to determine if a particular genetic sequence (1) is distantly related to life on Earth, indicating a shared ancestry due to lithological exchange, or (2) is unrelated to life on Earth, suggesting convergent origins of life on Mars. In this study, we validate prior work on nucleic acid extraction from cells deposited in Mars analog soils down to microbial concentrations (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.