Evidence map›Paper›PMID 31204690›Full record

ArticleActa crystallographica. Section F, Structural biology communications2019

Crystallization of a potassium ion channel and X-ray and neutron data collection.

Patricia S Langan, Venu Gopal Vandavasi, Brendan Sullivan, Joel Harp, Kevin Weiss, Leighton Coates

Open access · greenAbstract read
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Ion permeation in potassium ion channels.Acta crystallographica. Section D, Structural biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Patricia S LanganNeutron Scattering Division, Neutron Sciences Directorate, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, TN 37831, USA.
Venu Gopal VandavasiNeutron Scattering Division, Neutron Sciences Directorate, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, TN 37831, USA.
Brendan SullivanNeutron Scattering Division, Neutron Sciences Directorate, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, TN 37831, USA.ORCID 0000-0001-5271-8821
Joel HarpDepartment of Biochemistry and Center for Structural Biology, Vanderbilt University School of Medicine, 1161 21st Avenue South, Nashville, TN 37232, USA.
Kevin WeissNeutron Scattering Division, Neutron Sciences Directorate, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, TN 37831, USA.ORCID 0000-0002-6486-8007
Leighton CoatesNeutron Scattering Division, Neutron Sciences Directorate, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, TN 37831, USA.ORCID 0000-0003-2342-049X
Oak Ridge National Laboratory · USVanderbilt University · US

Funding

Computational Tools for Neutron Protein CrystallographyR01GM071939 · NIGMS · UT-BATTELLE, LLC-OAK RIDGE NATIONAL LAB · PI COATES, LEIGHTON · 2004 to 2019
$4.3M
National Institutes of Health R01-GM071939NIGMS NIH HHS R01 GM071939
6 · The paper itself

Abstract

The mechanism by which potassium ions are transported through ion channels is currently being investigated by several groups using many different techniques. Clarification of the location of water molecules during transport is central to understanding how these integral membrane proteins function. Neutrons have a unique sensitivity to both hydrogen and potassium, rendering neutron crystallography capable of distinguishing waters from K

Indexed as

NeutronsBacillus cereusBacterial ProteinsCrystallography, X-RayModels, MolecularPotassium ChannelsProtein ConformationBacterial ProteinsPotassium Channelsion channelsmembrane proteinsneutron diffractionX-ray diffraction

Identifiers

PMID31204690
PMCPMC6572099
OpenAlexW2945787865

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.