Evidence map›Paper›PMID 31204486›Full record

SynthesisCartilage2021

Bipolar Cartilage Lesions of the Knee: A Systematic Review of Techniques, Outcomes, and Complications.

Heath P Melugin, Christopher D Bernard, Christopher L Camp, Daniel B F Saris, Aaron J Krych

Abstract readSystematic Review
In one paragraph

Synthesis in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Heath P MeluginDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Christopher D BernardDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Christopher L CampDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-3058-7327
Daniel B F SarisDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Aaron J KrychDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-3248-8007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this systematic review was to determine (1) treatment options for bipolar cartilage lesions of the knee, (2) patient-reported outcomes following various surgical treatments, and (3) complication and failure rates following surgery.

designA literature search of PubMed, the Cochrane Library, and CINHAL was performed using PRISMA guidelines. Patients were included if they had bipolar cartilage lesions of the knee treated surgically. Lesion characteristics, surgical technique, patient-reported outcomes, complication rates, failure rates, and survivorship were recorded.

resultsFourteen studies yielded 301 knees treated surgically. Patient age ranged from 15 to 74 years. Surgical techniques included 138 autologous chondrocyte implantation (ACI), 156 osteochondral allograft transplantation (OCA), and 7 osteochondral autograft transfer system (OATS). Seven studies reported a concomitant procedure rate that ranged from 0% to 88%. Eight studies reported that both reciprocal lesions received surgical treatment, while 6 studies did not specify. Lesion size ranged from 1 to 41 cm

conclusionsBipolar cartilage lesions of the knee typically involve a large surface area and are most commonly treated with ACI or OCA, while OATS may be an option for smaller lesions. Improvements in mid-term patient-reported outcomes were reported for all surgical procedures and they can be performed safely with a low rate of major complications.

Indexed as

AdolescentAdultAgedBone TransplantationCartilageCartilage, ArticularCartilage DiseasesChondrocytesHumansIntra-Articular FracturesKnee JointMiddle AgedOrthopedic ProceduresRecovery of FunctionTransplantation, AutologousTreatment Outcomeautologous chondrocyte implantationbipolar cartilage lesionosteochondral allograftosteochondral autograft transfer

Identifiers

PMID31204486
PMCPMC8808778

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.