Evidence map›Paper›PMID 31203609›Full record

ArticleJournal of the American Chemical Society2019

Chloride Control of the Mechanism of Human Serum Ceruloplasmin (Cp) Catalysis.

Shiliang Tian, Stephen M Jones, Anex Jose, Edward I Solomon

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Molecular Functions of Ceruloplasmin in Metabolic Disease Pathology.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shiliang TianDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0002-9830-5480
Stephen M JonesDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0003-2045-1661
Anex JoseDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0002-4924-7886
Edward I SolomonDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0003-0291-3199
Stanford University · US

Funding

Structure/Function Correlations Over Copper EnzymesR01DK031450 · NIDDK · STANFORD UNIVERSITY · PI EDWARD I SOLOMON · 1986 to 2026
$8.7M
Understanding the reactivity of the most complex multicopper oxidase ceruloplasmin: insight into the reaction intermediates, mechanism and the roles of the additional type 1 copper sitesF32GM122174 · NIGMS · STANFORD UNIVERSITY · PI TIAN, SHILIANG · 2017 to 2019
$176k
NIDDK NIH HHS R01 DK031450NIGMS NIH HHS F32 GM122174
6 · The paper itself

Abstract

Unraveling the mechanism of ceruloplasmin (Cp) is fundamentally important toward understanding the pathogenesis of metal-mediated diseases and metal neurotoxicity. Here we report that Cl

Indexed as

Catalytic DomainCeruloplasminChloridesCrystallography, X-RayElectron TransportHumansModels, MolecularOxidation-ReductionOxygenProtein ConformationCeruloplasminChloridesOxygen

Identifiers

PMID31203609
PMCPMC6657493
OpenAlexW2952500815

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.