Evidence map›Paper›PMID 31203487›Full record

ArticleBreast cancer research and treatment2019

Preliminary results of computer-aided diagnosis for magnetic resonance imaging of solid breast lesions.

Qiujie Yu, Kuan Huang, Ye Zhu, Xiaodan Chen, Wei Meng

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In one paragraph

Article in Breast cancer research and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Qiujie YuRadiology Department, Harbin Medical University, The Third Affiliated Hospital of Harbin Medical University, 150 Haping Road, Harbin, 150081, Heilongjiang, China.
Kuan HuangDepartment of Computer Science, Utah State University, Old Main Hill, Logan, Utah, 84322, USA.
Ye ZhuDepartment of Obstetrics and Gynecology, Peking University People's Hospital, No.11 Xizhimen South Street, Xicheng District, Beijing, 100044, China.
Xiaodan ChenDepartment of Computer Technology, Harbin Institute of Technology University, 92 West street, Harbin, 150000, Heilongjiang, China.
Wei MengRadiology Department, Harbin Medical University, The Third Affiliated Hospital of Harbin Medical University, 150 Haping Road, Harbin, 150081, Heilongjiang, China. articlemengwei@163.com.ORCID http://orcid.org/0000-0002-3745-4036
Harbin Medical University · CNHarbin Institute of Technology · CNPeking University · CNUtah State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe present study aimed to determine suitable optimal classifiers and investigate the general applicability of computer-aided diagnosis (CAD) to compare magnetic resonance (MR)-CAD with MR imaging (MRI) in distinguishing benign from malignant solid breast masses.

methodsWe analyzed a total of 251 patients (mean age: 44.8 ± 12.3 years; range: 21-81 years) with 274 breast masses (154 benign masses, 120 malignant masses) using a Gaussian mixture model and a random forest machine model for segmentation and classification.

resultsThe diagnostic performance of MRI alone and MRI plus CAD were compared with respect to sensitivity, specificity, and area under the curve (AUC), using receiver operating characteristic curve analysis. The discriminating power to detect malignancy using MR-CAD with an AUC of 0.955 (sensitivity was 95.8% and the specificity was 92.9%) was significantly higher than that of MRI alone with an AUC of 0.785 (sensitivity was 71.7% and the specificity was 85.7%).

conclusionCAD is feasible to differentiate breast lesions, and it can complement MRI, thereby making it easier to diagnose breast lesions and obviating the need for unnecessary biopsies.

Indexed as

Diagnosis, Computer-AssistedMagnetic Resonance ImagingAdultAgedAged, 80 and overAlgorithmsBiopsyBreast DiseasesBreast NeoplasmsDiagnosis, DifferentialFemaleHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMiddle AgedROC CurveBreast lesionsComputer-aided diagnosisGaussian mixtureMRIRandom forest

Identifiers

PMID31203487
OpenAlexW2951795602

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.