ReviewCurrent urology reports2019
Sperm Morphology: History, Challenges, and Impact on Natural and Assisted Fertility.
Review in Current urology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Probiotics supplementation in the treatment of male infertility: A Systematic Review.JBRA assisted reproduction · 2024Pooled it
- Evaluation of technicians' ability to accurately identify sperm morphology through EQA programs in China: a 5-year nationwide study (2019-2024).Asian journal of andrology · 2026Article
- Sperm-Associated Mercury Species Levels Determine Its Impairment: Evidence from Paired Analyses of Whole Semen and Seminal Plasma.Biological trace element research · 2026Article
- SPACA4 regulates the structure and molecular basis of spermatid maturation and ultimately affects sperm quality in mice.Asian journal of andrology · 2026Article
- Article
- Sperm Testing in Assisted Reproductive Technology: Diagnosis and Outcome Prediction.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- TSSKL is essential for sperm mitochondrial morphogenesis and male fertility in moths.PLoS genetics · 2025Article
- Semen Characteristics and Embryo Outcomes in IVF.Journal of family & reproductive health · 2025Article
- Evaluation of structural problems in the application of strict criteria for sperm morphology assessment.Andrology · 2025Article
- Assessment of Boar Semen Morphology and Morphometry.Methods in molecular biology (Clifton, N.J.) · 2025Review
- Untargeted metabolomics fingerprints in seminal plasma of patients with abnormal sperm morphology using high-performance liquid chromatography and mass spectrometry.Frontiers in molecular biosciences · 2025Article
- Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece.Frontiers in cell and developmental biology · 2025Article
- Current and Future Applications of Artificial Intelligence to Diagnose and Treat Male Infertility.Advances in experimental medicine and biology · 2025Review
- Article
- High rate of isolated teratospermia in a population of fertile men and the questionable clinical utility of sperm morphology.F&S reports · 2024Article
- Sperm morphology by strict criteria does not predict clinical pregnancy rate following intra-uterine insemination.Arab journal of urology · 2024Article
- Stain-Free Sperm Analysis and Selection for Intracytoplasmic Sperm Injection Complying with WHO Strict Normal Criteria.Biomedicines · 2023Article
- Trends in semen parameters of infertile men in South Africa and Nigeria.Scientific reports · 2023Article
- Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations.The world journal of men's health · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThe classification of morphologically normal sperm has been progressively redefined. Concurrently, our understanding of the significance of sperm morphology in relation to male factor infertility has evolved. In this review, we will discuss the evolution of sperm morphology assessment and factors that contribute to its measurement variability. We will examine the impact of sperm morphology on natural pregnancy, IUI, IVF, and ICSI outcomes. RECENT
findingsThere is a lack of consensus on sperm morphology classification, technique, and inter-observer grading variability. Current evidence suggests sperm morphology has low predictive value for pregnancy success, for both natural and assisted reproduction. Additionally, the threshold for what is considered an adequate percentage of morphologically normal sperm has changed over time. These variables have called into question the relevance of this variable in predicting fertility outcomes. Our understanding of the impact of sperm morphology on reproductive outcomes continues to evolve and seems to play less of a role than initially thought.
Indexed as
Identifiers
31203470What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.