ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
Ultrasound non-invasive intracranial pressure assessment in paediatric neurocritical care: a pilot study.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- 3D Freehand Ultrasound Imaging of Optic Nerve Sheath.Investigative radiology · 2026Article
- Clinical Applications of Point-of-Care and Diagnostic Transcranial Doppler in the Pediatric Acute Care Setting: A Scoping Review.Neurocritical care · 2026Article
- Optic Nerve Sheath Diameter as a Prognostic Tool for Mortality in Intensive Care Unit Patients.Cureus · 2026Article
- Evaluation of near-infrared spectroscopy, transcranial Doppler, and ophthalmic ultrasound measurements in critically Ill pediatric patients with increased intracranial pressure.Frontiers in pediatrics · 2025Article
- Evaluation of monitoring critical ill children with traumatic brain injury.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025Article
- Point-of-care brain ultrasound and transcranial doppler or color-coded doppler in critically ill neonates and children.European journal of pediatrics · 2024Review
- Non-Invasive Quantitative Approximation of Intracranial Pressure in Pediatric Idiopathic Intracranial Hypertension Based on Point-of-Care Ultrasound of the Optic Nerve Sheath Diameter.Brain sciences · 2023Article
- Optic nerve sheath diameter and pulsatility index for the diagnosis and follow-up in pediatric traumatic brain injury: a prospective observational cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Observational
- Optic Nerve Ultrasound Evaluation in Children: A Review.Diagnostics (Basel, Switzerland) · 2023Review
- The role of sonographic optic nerve sheath diameter measurements in pediatric head trauma.Journal of ultrasound · 2022Article
- Transcranial Doppler Ultrasound, a Review for the Pediatric Intensivist.Children (Basel, Switzerland) · 2022Review
- Optic Nerve Sheath Diameter Ultrasound: A Non-Invasive Approach to Evaluate Increased Intracranial Pressure in Critically Ill Pediatric Patients.Diagnostics (Basel, Switzerland) · 2022Review
- Practice Recommendations for Transcranial Doppler Ultrasonography in Critically Ill Children in the Pediatric Intensive Care Unit: A Multidisciplinary Expert Consensus Statement.Journal of pediatric intensive care · 2021Article
- Continuous Monitoring of Cerebral Autoregulation in Children Supported by Extracorporeal Membrane Oxygenation: A Pilot Study.Neurocritical care · 2021Observational
- Dynamic Optic Nerve Sheath Diameter (ONSD) guided management of raised intracranial pressure in pediatric acute liver failure.Hepatology international · 2021Article
- Is Ocular Sonography a Reliable Method for the Assessment of Elevated Intracranial Pressure in Children?Journal of pediatric intensive care · 2021Review
- Estimating intracranial pressure using pulsatile cerebral blood flow measured with diffuse correlation spectroscopy.Biomedical optics express · 2020Article
- Ultrasonographic measurement of optic nerve sheath diameter during laparoscopic surgeries in pediatric patients: An observational study.Journal of anaesthesiology, clinical pharmacologyArticle
Corrections and comments
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Authors and funding
11 authors at 9 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe assessment of intracranial pressure (ICP) is essential in the management of neurocritical care paediatric patients. The gold standard for invasive ICP is an intraventricular catheter or intraparenchymal microsensor but is invasive and carries some risks. Therefore, a non-invasive method for measuring ICP (nICP) would be desirable especially in the paediatric population. The aim of this study is to assess the relationship between ICP and different ultrasound-based methods in neurocritical care paediatric patients.
methodsChildren aged < 16 years with indication for invasive ICP monitoring were prospectively enrolled. The following non-invasive methods were compared with the invasive gold standard: optic nerve sheath diameter ultrasound (ONSD)-derived nICP (nICP
resultsWe analysed 107 measurements from 10 paediatric patients. Results from linear regression demonstrated that, among the nICP methods, ONSD has the best correlation with ICP (r = 0.852 (p < 0.0001)). Results from receiving operator curve analysis demonstrated that using a threshold of 15 mmHg, ONSD has and area under the curve (AUC) of 0.94 (95% CI = 0.892-0.989), with best threshold at 3.85 mm (sensitivity = 0.811; specificity = 0.939).
conclusionsOur preliminary results suggested that ONSD ultrasonography presents the best accuracy to assess ICP among the methods studied. Given its non-invasiveness, repeatability and safety, this technique has the potential of representing a valid option as non-invasive tool to assess the risk of intracranial hypertension in the paediatric population.
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