Evidence map›Paper›PMID 31202887›Full record

ReviewJournal of molecular biology2019

Mechanisms of Non-segmented Negative Sense RNA Viral Antagonism of Host RIG-I-Like Receptors.

Daisy W Leung

Open access · greenAbstract readReview
In one paragraph

Review in Journal of molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Daisy W LeungDivision of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: dwleung@wustl.edu.
Washington University in St. Louis · US

Funding

Virology BSL4 CoreP01AI120943 · NIAID · WASHINGTON UNIVERSITY · PI Gaya K. Amarasinghe · 2016 to 2026
$30.2M
Mechanisms of actin cytoskeleton modulation by PneumovirusesR01AI140758 · NIAID · UNIVERSITY OF KENTUCKY · PI DUTCH, REBECCA E., LEUNG, DAISY W · 2018 to 2022
$3.3M
STRUCTURAL BASIS FOR IMMUNE EVASION BY RSV NON-STRUCTURAL PROTEINSR01AI107056 · NIAID · WASHINGTON UNIVERSITY · PI LEUNG, DAISY W · 2013 to 2017
$1.9M
NIAID NIH HHS P01 AI120943NIAID NIH HHS R01 AI107056NIAID NIH HHS R01 AI140758
6 · The paper itself

Abstract

The pattern recognition receptors RIG-I-like receptors (RLRs) are critical molecules for cytosolic viral recognition and for subsequent activation of type I interferon production. The interferon signaling pathway plays a key role in viral detection and generating antiviral responses. Among the many pathogens, the non-segmented negative sense RNA viruses target the RLR pathway using a variety of mechanisms. Here, I review the current state of knowledge on the molecular mechanisms that allow non-segmented negative sense RNA virus recognition and antagonism of RLRs.

Indexed as

AnimalsDEAD Box Protein 58HumansInterferon Type IReceptors, Pattern RecognitionRNA, ViralSignal TransductionDEAD Box Protein 58Interferon Type IReceptors, Pattern RecognitionRNA, Viralhost-viral interactionsIFN antagonismnon-segmented negative sense RNA virusesRIG-I-like receptors

Identifiers

PMID31202887
PMCPMC6879798
OpenAlexW2951209779

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.