Evidence map›Paper›PMID 31202272›Full record

ArticleBMC anesthesiology2019

Intraoperative management of brain-dead organ donors by anesthesiologists during an organ procurement procedure: results from a French survey.

Benoit Champigneulle, Arthur Neuschwander, Régis Bronchard, Gersende Favé, Julien Josserand, Benjamin Lebas, Olivier Bastien, Romain Pirracchio, SFAR research network

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07166991 (Impact of a Specific Anesthetic Strategy on Intraoperative Hemodynamic Stability During Organ Procurement in Brain Dead Donor), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07166991 phase3recruitingnot on this mapstarted 2026, after this paper: background citation

Impact of a Specific Anesthetic Strategy on Intraoperative Hemodynamic Stability During Organ Procurement in Brain Dead Donor: An Open-label Multicenter Randomized and Controlled Trial

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2026 to 2029Enrolled270ConditionsBrain-dead Organ DonorsArmsVolatile anesthetic, Opioid Anesthesia, Intraoperative brain-dead donor management
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Donor Evaluation Protocol for Live and Deceased Donors.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Benoit ChampigneulleAnesthesiology and Intensive Care Department, European Hospital Georges-Pompidou, Assistance Publique - Hôpitaux de Paris (AP-HP), 20 rue Leblanc, 75015, Paris, France.
Arthur NeuschwanderAnesthesiology and Intensive Care Department, European Hospital Georges-Pompidou, Assistance Publique - Hôpitaux de Paris (AP-HP), 20 rue Leblanc, 75015, Paris, France.
Régis BronchardAgence de la Biomédecine, Direction Prélèvement Greffe Organes-Tissus, Saint-Denis La Plaine, France.
Gersende FavéAnesthesiology and Intensive Care Department, European Hospital Georges-Pompidou, Assistance Publique - Hôpitaux de Paris (AP-HP), 20 rue Leblanc, 75015, Paris, France.
Julien JosserandAnesthesiology and Intensive Care Department, European Hospital Georges-Pompidou, Assistance Publique - Hôpitaux de Paris (AP-HP), 20 rue Leblanc, 75015, Paris, France.
Benjamin LebasAnesthesiology and Intensive Care Department, Hautepierre Hospital, Strasbourg, France.
Olivier BastienAgence de la Biomédecine, Direction Prélèvement Greffe Organes-Tissus, Saint-Denis La Plaine, France.
Romain PirracchioAnesthesiology and Intensive Care Department, European Hospital Georges-Pompidou, Assistance Publique - Hôpitaux de Paris (AP-HP), 20 rue Leblanc, 75015, Paris, France. romain.pirracchio@aphp.fr.ORCID 0000-0002-7007-4908
SFAR research network
Assistance Publique – Hôpitaux de Paris · FRAgence de la Biomédecine · FRDélégation Paris 5 · FRHôpital d'Hautepierre · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed at describing usual anesthetic practices for brain-dead donors (BDD) during an organ procurement (OP) procedure and to assess the knowledge and self-confidence of French anesthesiologists with this practice.

methodsAn electronic and anonymous survey with closed-questions about anesthetic management of BDD was distributed to French anesthesiologists via the mailing list of the French Society of Anesthesiology and Intensive Care Medicine.

resultsFour hundred fifty-eight responses were analyzed. Respondents were mainly attending physicians with more than 10 years of clinical experience. 78% of them declared being cognizant of guidelines regarding management of BDD. Advanced hemodynamic monitoring and endocrine substitution were rarely considered by respondents (31 and 35% of respondents, respectively). 98% of the respondents used crystalloids for fluid resuscitation. During the procedure, use of neuromuscular blockers, opioids and sedative agents were considered by respectively 84, 61 and 27% of the respondents. A very high level of agreement (10 [8-10], on a ten-points Likert-style scale) was reported concerning the expected impact of intraoperative anesthetic management on the primary function of grafts.

conclusionsDeclared anesthetic practice appeared in accordance with guidelines concerning organ donor management in the ICU. Further studies are needed to evaluate the specific impact of intraoperative management during this procedure and thus the need for specific anesthetic guidelines.

Indexed as

AnesthesiologistsBrain DeathClinical CompetenceHealth Care SurveysAnesthesiaFranceHealth Knowledge, Attitudes, PracticeHumansTissue and Organ ProcurementAnesthesiaBrain-dead donorsOrgan procurementSurvey

Identifiers

PMID31202272
PMCPMC6570868
OpenAlexW2952555123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.