Evidence map›Paper›PMID 31201698›Full record

ArticleEnvironmental science and pollution research international2019

Maternal exposure to bisphenol A during pregnancy interferes testis development of F1 male mice.

Yuanyuan Wei, Chao Han, Yumeng Geng, Yuqing Cui, Yongzhan Bao, Wanyu Shi, Xiuhui Zhong

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Redox mechanisms of environmental toxicants on male reproductive function.Frontiers in cell and developmental biology · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yuanyuan WeiInstitute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Baoding, 071001, Hebei, China.
Chao HanInstitute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Baoding, 071001, Hebei, China.
Yumeng GengInstitute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Baoding, 071001, Hebei, China.
Yuqing CuiInstitute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Baoding, 071001, Hebei, China.
Yongzhan BaoInstitute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Baoding, 071001, Hebei, China.
Wanyu ShiInstitute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Baoding, 071001, Hebei, China. shiwanyu2010@126.com.
Xiuhui ZhongInstitute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Baoding, 071001, Hebei, China. zxh8078@163.com.
Hebei Agricultural University · CN

Funding

National Natural Science Foundation of China No.31872506
6 · The paper itself

Abstract

This study was conducted to investigate the effects of maternal exposure to bisphenol A (BPA) on testis development of F1 male mice. The BPA exposure model of pregnant mice was prepared by intragastric administration of BPA at the doses of 0, 2.5, 5, 10, 20, and 40 mg/kg/day at gestation day (GD) 0.5-17.5. The testis index of the offspring mice was calculated at postnatal day (PND) 21 and PND 56. The results showed that maternal exposure to 20 mg/kg BPA during pregnancy significantly increased the testicular index of F1 males at PND 21, and 40 mg/kg BPA significantly decreased the testicular index of F1 males at PND 56 (P < 0.01). BPA significantly reduced serum testosterone (T) and estradiol (E

Indexed as

AnimalsBenzhydryl CompoundsBisphenol A CompoundsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BEndocrine DisruptorsEstradiolEstrogen Receptor alphaEstrogen Receptor betaFemaleMaleMaternal ExposureMicePhenolsPregnancyPrenatal Exposure Delayed EffectsBCL2 protein, humanBenzhydryl Compoundsbisphenol ABisphenol A CompoundsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BEndocrine DisruptorsESR1 protein, humanEstradiolEstrogen Receptor alphaEstrogen Receptor betaPhenolsProto-Oncogene Proteins c-bcl-2Receptors, EstrogenTestosteroneApoptosisBisphenol ADNA methyltransferaseMale offspringReproduction

Identifiers

PMID31201698
OpenAlexW2950370287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.