Evidence map›Paper›PMID 31201649›Full record

ReviewJournal of industrial microbiology & biotechnology2019

Prebiotics: tools to manipulate the gut microbiome and metabolome.

Fatima Enam, Thomas J Mansell

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of industrial microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. The role of Micro-biome engineering in enhancing Food safety and quality.Biotechnology notes (Amsterdam, Netherlands) · 2025
    Review
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  14. Prebiotics: Ignored player in the fight against cancer.Cancer reports (Hoboken, N.J.) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fatima EnamDepartment of Chemical and Biological Engineering, Iowa State University, Ames, IA, 50011, USA.
Thomas J MansellDepartment of Chemical and Biological Engineering, Iowa State University, Ames, IA, 50011, USA. mansell@iastate.edu.ORCID http://orcid.org/0000-0001-8807-4570

Funding

Iowa State University Startup funds
6 · The paper itself

Abstract

The human gut is an ecosystem comprising trillions of microbes interacting with the host. The composition of the microbiota and their interactions play roles in different biological processes and in the development of human diseases. Close relationships between dietary modifications, microbiota composition and health status have been established. This review focuses on prebiotics, or compounds which selectively encourage the growth of beneficial bacteria, their mechanisms of action and benefits to human hosts. We also review advances in synthesis technology for human milk oligosaccharides, part of one of the most well-characterized prebiotic-probiotic relationships. Current and future research in this area points to greater use of prebiotics as tools to manipulate the microbial and metabolic diversity of the gut for the benefit of human health.

Indexed as

Gastrointestinal MicrobiomeMetabolomeAnimalsBacteriaHumansOligosaccharidesPrebioticsProbioticsOligosaccharidesPrebioticsGut microbiomeHuman milk oligosaccharidesPrebiotics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.