ArticleEuropean radiology2019
USPIO-enhanced MRI of pelvic lymph nodes at 7-T: preliminary experience.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Systematic Review of Magnetic Resonance Lymphangiography From a Technical Perspective.Journal of magnetic resonance imaging : JMRI · 2021Pooled it
- Ferumoxtran-10-enhanced MRI for pre-operative metastatic lymph node detection in pancreatic, duodenal, or periampullary adenocarcinoma.European radiology · 2024Trial
- Summary from the 2025 International Society for Magnetic Resonance in Medicine workshop on body MRI: Unsolved problems and unmet needs.Magnetic resonance in medicine · 2026Review
- Evaluation of a Novel Gd-FAPI Dimer Molecular Probe Targeting Fibroblast Activation Protein for Imaging of Solid Tumors.Molecular pharmaceutics · 2025Article
- Advances in molecular imaging and targeted therapeutics for lymph node metastasis in cancer: a comprehensive review.Journal of nanobiotechnology · 2024Review
- Free-breathing high-resolution respiratory-gated radial stack-of-stars magnetic resonance imaging of the upper abdomen at 7 T.NMR in biomedicine · 2024Article
- Advancing MRI with magnetic nanoparticles: a comprehensive review of translational research and clinical trials.Nanoscale advances · 2024Review
- The diagnosis and management of small and indeterminate lymph nodes in papillary thyroid cancer: preoperatively and intraoperatively.Frontiers in endocrinology · 2024Review
- The development process of 'fit-for-purpose' imaging biomarkers to characterize the tumor microenvironment.Frontiers in medicine · 2024Review
- Functional roles of magnetic nanoparticles for the identification of metastatic lymph nodes in cancer patients.Journal of nanobiotechnology · 2023Review
- A vision of 14 T MR for fundamental and clinical science.Magma (New York, N.Y.) · 2023Review
- Carboxylated superparamagnetic FeBMC cancer · 2023Article
- Ultra-high-field MR in Prostate cancer: Feasibility and Potential.Magma (New York, N.Y.) · 2022Review
- Validation of In Vivo Nodal Assessment of Solid Malignancies with USPIO-Enhanced MRI: A Workflow Protocol.Methods and protocols · 2022Article
- 7 Tesla and Beyond: Advanced Methods and Clinical Applications in Magnetic Resonance Imaging.Investigative radiology · 2021Review
- The Role of Magnetic Resonance Imaging in (Future) Cancer Staging: Note the Nodes.Investigative radiology · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeTo evaluate the technical feasibility of high-resolution USPIO-enhanced magnetic resonance imaging of pelvic lymph nodes (LNs) at ultrahigh magnetic field strength. MATERIALS AND
methodsThe ethics review board approved this study and written informed consent was obtained from all patients. Three patients with rectal cancer and three selected patients with (recurrent) prostate cancer were examined at 7-T 24-36 h after intravenous ferumoxtran-10 administration; rectal cancer patients also received a 3-T MRI. Pelvic LN imaging was performed using the TIAMO technique in combination with water-selective multi-GRE imaging and lipid-selective GRE imaging with a spatial resolution of 0.66 × 0.66 × 0.66mm
resultsHigh-resolution 7-T MR gradient-echo imaging was obtained robustly in all patients without suffering from RF-related signal voids. USPIO signal decay in LNs was visualized using computed TE imaging at TE = 8 ms and an R
conclusionUSPIO-enhanced MRI of the pelvis at 7-T is technically feasible and offers opportunities for detecting USPIO uptake in normal-sized LNs, due to its high intrinsic signal-to-noise ratio and spatial resolution. KEY POINTS: • USPIO-enhanced MRI at 7-T can indicate USPIO uptake in lymph nodes based on computed TE images. • Our method promises a high spatial resolution for pelvic lymph node imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.