ArticleJournal of neurology2019
Vestibular dysfunction in acute traumatic brain injury.
Article in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Audiovestibular Dysfunction in Alcohol Use Disorder: A Systematic Review of Human Primary Clinical Evidence.International journal of molecular sciences · 2026Pooled it
- Are Tai Chi and Qigong effective in the treatment of traumatic brain injury? A systematic review.BMC complementary medicine and therapies · 2024Pooled it
- Prevalence of Vestibular Dysfunction in Children With Neurological Disabilities: A Systematic Review.Frontiers in neurology · 2019Pooled it
- Trial
- What are the views of those participating in a trial investigating acute post-traumatic benign paroxysmal positional vertigo? A qualitative study.Brain injury · 2025Trial
- Cardiogenic vertigo: clinical characteristics and predictors of long-term prognosis.Journal of neurology · 2026Article
- Development and Evaluation of a Novel Transcanal Catheter for Delivery of Hypothermia to the Inner Ear.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2025Article
- The International Classification of Vestibular Disorders: Achievements, challenges, and future directions.Journal of vestibular research : equilibrium & orientation · 2025Review
- Exploring the Link Between Traumatic Brain Injury and Benign Paroxysmal Positional Vertigo.Cureus · 2025Review
- Balance recovery and its link to vestibular agnosia in traumatic brain injury: a longitudinal behavioural and neuro-imaging study.Journal of neurology · 2025Article
- Current and prospective roles of magnetic resonance imaging in mild traumatic brain injury.Brain communications · 2025Review
- From acute injury to chronic comorbidity: Interrupted time series modeling of traumatic brain injury impact among post-9/11 veterans.PloS one · 2025Article
- Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation.CNS & neurological disorders drug targets · 2025Review
- Connectivity of the insular subdivisions differentiates posttraumatic headache-associated from nonheadache-associated mild traumatic brain injury: an arterial spin labelling study.The journal of headache and pain · 2024Article
- A review of the personality traits in post-concussion syndrome.Acta neurologica Belgica · 2024Review
- Treating benign paroxysmal positional vertigo in acute traumatic brain injury: a prospective, randomised clinical trial assessing safety, feasibility, and efficacy.BMJ neurology open · 2024Article
- Dizziness-Related Disability One Year after a Mild-to-Moderate TBI-A Follow-Up Study.Journal of clinical medicine · 2023Article
- Post-Traumatic Craniocervical Disorders From a Postural Control Perspective: A Narrative Review.Brain & NeuroRehabilitation · 2023Review
- Article
- A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation.Frontiers in human neuroscience · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
Traumatic brain injury (TBI) is the commonest cause of disability in under-40-year-olds. Vestibular features of dizziness (illusory self-motion) or imbalance which affects 50% of TBI patients at 5 years, increases unemployment threefold in TBI survivors. Unfortunately, vestibular diagnoses are cryptogenic in 25% of chronic TBI cases, impeding therapy. We hypothesized that chronic adaptive brain mechanisms uncouple vestibular symptoms from signs. This predicts a masking of vestibular diagnoses chronically but not acutely. Hence, defining the spectrum of vestibular diagnoses in acute TBI should clarify vestibular diagnoses in chronic TBI. There are, however, no relevant acute TBI data. Of 111 Major Trauma Ward adult admissions screened (median 38-years-old), 96 patients (87%) had subjective dizziness (illusory self-motion) and/or objective imbalance were referred to the senior author (BMS). Symptoms included: feeling unbalanced (58%), headache (50%) and dizziness (40%). In the 47 cases assessed by BMS, gait ataxia was the commonest sign (62%) with half of these cases denying imbalance when asked. Diagnoses included BPPV (38%), acute peripheral unilateral vestibular loss (19%), and migraine phenotype headache (34%), another potential source of vestibular symptoms. In acute TBI, vestibular signs are common, with gait ataxia being the most frequent one. However, patients underreport symptoms. The uncoupling of symptoms from signs likely arises from TBI affecting perceptual mechanisms. Hence, the cryptogenic nature of vestibular symptoms in TBI (acute or chronic) relates to a complex interaction between injury (to peripheral and central vestibular structures and perceptual mechanisms) and brain-adaptation, emphasizing the need for acute prospective, mechanistic studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.