ArticleBundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz2019
[Management of seasonal influenza in 2017/2018 at a German tertiary-care hospital].
Article in Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract.Emerging microbes & infections · 2024Article
- Complications of influenza in 272 adult and pediatric patients in a German university hospital during the seasonal epidemic 2017-2018.Wiener medizinische Wochenschrift (1946) · 2022Article
- [SARS-CoV-2, influenza and norovirus infection : A direct epidemiologic comparison].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2022Article
- Extracorporeal Membrane Oxygenation Support for Influenza A: Retrospective Review of the Extracorporeal Life Support Organization Registry Comparing H1N1 With Other Subtypes.Critical care explorations · 2021Article
- Comparison of clinical characteristics and disease outcome of COVID-19 and seasonal influenza.Scientific reports · 2021Observational
- Management of patients with SARS-CoV-2 infections and of patients with chronic lung diseases during the COVID-19 pandemic (as of 9 May 2020) : Statement of the Austrian Society of Pneumology (ASP).Wiener klinische Wochenschrift · 2020Article
- [Statement of the Austrian Society of Pneumology (ASP)].Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift · 2020Review
- [Fatality and risk factors for severe courses of COVID-19 pneumonia].Der Pneumologe · 2020Review
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10 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are only few structured reports on inpatient management of a seasonal influenza epidemic.
objectivesA systematic description of a seasonal influenza patient population at a German university hospital to improve risk stratification and clinical care.
methodsIn this monocentric, retrospective observational study of the 2017/2018 influenza season at the University Medical Center Hamburg-Eppendorf, patients with confirmed influenza infection were included.
resultsOf all influenza swabs performed in the emergency department, 24% (n = 162/676) were positive. A total of 255 patients (median age 66 years) had an influenza infection (influenza A n = 79, influenza B n = 176); 27 (15.3%) were nosocomial infections. Of the 179 (70.2%) patients that were hospitalized, 51 (20%) received intensive medical care. Patients with subsequent need for intensive care had an elevated CRP level (69.5 mg/dl [SD 62.8] vs. 141.7 [SD 127.2] mg/dl) at the time of influenza diagnosis and more frequent infiltrates in X‑ray/CT of the thorax (n = 43 [33.6%] vs. n = 43 [84.3%]). Antiviral therapy with oseltamivir was administered for 74 (29.0%) patients and 11 (6.1%) patients were treated with extracorporeal membrane oxygenation (ECMO). Of the 23 (9.0%) patients who died, only four of them had been vaccinated (trivalent). Those four had an influenza B infection.
conclusionThe structured use of diagnostic tests (influenza PCR, X‑ray/CT chest and CRP) and antiviral therapy (oseltamivir) as well as targeted management of admission, intensive care capacities, and an increase in vaccination rates are important for improving patient care and optimizing the use of resources during seasonal influenza epidemics.
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