Evidence map›Paper›PMID 31201376›Full record

ArticleEuropean journal of human genetics : EJHG2020

CUGC for posterior polymorphous corneal dystrophy (PPCD).

Alice E Davidson, Nathaniel J Hafford-Tear, Lubica Dudakova, Amanda N Sadan, Nikolas Pontikos, Alison J Hardcastle, Stephen J Tuft, Petra Liskova

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of human genetics : EJHG, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Posterior Polymorphous Corneal Dystrophy in a Patient with a NovelInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Alice E DavidsonUCL Institute of Ophthalmology, London, EC1V 9EL, UK. alice.davidson@ucl.ac.uk.ORCID http://orcid.org/0000-0002-1816-6151
Nathaniel J Hafford-TearUCL Institute of Ophthalmology, London, EC1V 9EL, UK.
Lubica DudakovaFirst Faculty of Medicine, Research Unit for Rare Diseases, Department of Paediatrics and Adolescent Medicine, Charles University and General University Hospital in Prague, Ke Karlovu 2, 128 08, Prague 2, Czech Republic.
Amanda N SadanUCL Institute of Ophthalmology, London, EC1V 9EL, UK.
Nikolas PontikosUCL Institute of Ophthalmology, London, EC1V 9EL, UK.ORCID http://orcid.org/0000-0003-1782-4711
Alison J HardcastleUCL Institute of Ophthalmology, London, EC1V 9EL, UK.
Stephen J TuftUCL Institute of Ophthalmology, London, EC1V 9EL, UK.
Petra LiskovaFirst Faculty of Medicine, Research Unit for Rare Diseases, Department of Paediatrics and Adolescent Medicine, Charles University and General University Hospital in Prague, Ke Karlovu 2, 128 08, Prague 2, Czech Republic.ORCID http://orcid.org/0000-0001-7834-8486
University College London · GBCharles University · CZInstitute of Ophthalmology · MXMoorfields Eye Hospital · GB

Funding

Medical Research Council MR/S031820/1
6 · The paper itself

Abstract

Name of the disease (synonyms) CUGC for posterior polymorphous corneal dystrophy (PPCD).OMIM# of the disease 122000; 609141; 618031.Name of the analysed genes or DNA/chromosome segments OVOL2 (PPCD1); ZEB1 (PPCD3); GRHL2 (PPCD4).OMIM# of the gene(s) 616441; 189909; 608576. Review of the analytical and clinical validity as well as of the clinical utility of DNA-based testing for variants in theOVOL2, ZEB1andGRHL2gene(s) in a diagnostic setting, predictive and parental settings and for risk assesment in relatives.

Indexed as

Corneal Dystrophies, HereditaryDNA-Binding ProteinsGenetic TestingHumansPractice Guidelines as TopicSensitivity and SpecificityTranscription FactorsZinc Finger E-box-Binding Homeobox 1DNA-Binding ProteinsGRHL2 protein, humanOvol2 protein, humanTranscription FactorsZEB1 protein, humanZinc Finger E-box-Binding Homeobox 1

Identifiers

PMID31201376
PMCPMC6906511
OpenAlexW2949948076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.