Evidence map›Paper›PMID 31201324›Full record

ArticleNature communications2019

Deterministic processes structure bacterial genetic communities across an urban landscape.

J M Hassell, M J Ward, D Muloi, J M Bettridge, H Phan, T P Robinson, A Ogendo, T Imboma, J Kiiru, S Kariuki and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  4. Review
  5. Epidemiological connectivity between humans and animals across an urban landscape.Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 3 countries.

J M HassellInstitute of Infection and Global Health, University of Liverpool, Leahurst Campus, Chester High Road, Neston, CH64 7TE, UK. hassell.jm@gmail.com.ORCID http://orcid.org/0000-0002-4710-2827
M J WardCentre for Immunity, Infection and Evolution, University of Edinburgh, EH9 3FL, Edinburgh, UK.
D MuloiInternational Livestock Research Institute, 30709, Nairobi, Kenya.
J M BettridgeInstitute of Infection and Global Health, University of Liverpool, Leahurst Campus, Chester High Road, Neston, CH64 7TE, UK.
H PhanNuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, OX3 9DU, Oxford, UK.
T P RobinsonFood and Agriculture Organization of the United Nations, 00153, Rome, Italy.
A OgendoInternational Livestock Research Institute, 30709, Nairobi, Kenya.
T ImbomaNational Museums of Kenya, 40658, Nairobi, Kenya.
J KiiruKenya Medical Research Institute, 54840, Nairobi, Kenya.
S KariukiKenya Medical Research Institute, 54840, Nairobi, Kenya.
M BegonInstitute of Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK.
E K Kang'etheUniversity of Nairobi, 29053, Nairobi, Kenya.
M E J WoolhouseCentre for Immunity, Infection and Evolution, University of Edinburgh, EH9 3FL, Edinburgh, UK.ORCID http://orcid.org/0000-0003-3765-8167
E M FèvreInstitute of Infection and Global Health, University of Liverpool, Leahurst Campus, Chester High Road, Neston, CH64 7TE, UK. Eric.Fevre@liverpool.ac.uk.
University of Liverpool · GBCentre for Immunity, Infection and Evolution · GBJohn Radcliffe Hospital · GBKenya Medical Research Institute · KEFood and Agriculture Organization of the United Nations · ITInternational Livestock Research Institute · KENational Museums of Kenya · KEUniversity of Nairobi · KE

Funding

Medical Research Council G1100783Medical Research Council MR/R015090/1RCUK | Medical Research Council (MRC) G1100783/1Wellcome Trust
6 · The paper itself

Abstract

Land-use change is predicted to act as a driver of zoonotic disease emergence through human exposure to novel microbial diversity, but evidence for the effects of environmental change on microbial communities in vertebrates is lacking. We sample wild birds at 99 wildlife-livestock-human interfaces across Nairobi, Kenya, and use whole genome sequencing to characterise bacterial genes known to be carried on mobile genetic elements (MGEs) within avian-borne Escherichia coli (n = 241). By modelling the diversity of bacterial genes encoding virulence and antimicrobial resistance (AMR) against ecological and anthropogenic forms of urban environmental change, we demonstrate that communities of avian-borne bacterial genes are shaped by the assemblage of co-existing avian, livestock and human communities, and the habitat within which they exist. In showing that non-random processes structure bacterial genetic communities in urban wildlife, these findings suggest that it should be possible to forecast the effects of urban land-use change on microbial diversity.

Indexed as

Adaptation, BiologicalAnimalsAnimals, WildBiodiversityBirdsEscherichia coliGenes, BacterialHumansInterspersed Repetitive SequencesKenyaLivestockMicrobiotaModels, BiologicalUrban HealthUrbanizationWhole Genome Sequencing

Identifiers

PMID31201324
PMCPMC6572833
OpenAlexW2952089337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.