ArticleNature communications2019
Genomic signatures of heterokaryosis in the oomycete pathogen Bremia lactucae.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 75 citations in OpenAlex.
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- Complete telomere-to-telomere genomes uncover virulence evolution conferred by chromosome fusion in oomycete plant pathogens.Nature communications · 2024Article
- Worldwide forest surveys reveal forty-three new species inStudies in mycology · 2024Article
- The genome of the oomycete Peronosclerospora sorghi, a cosmopolitan pathogen of maize and sorghum, is inflated with dispersed pseudogenes.G3 (Bethesda, Md.) · 2023Article
- Phylogeography and population structure of the global, wide host-range hybrid pathogen Phytophthora × cambivora.IMA fungus · 2023Article
- Extensive morphological and behavioural diversity among fourteen new and seven described species inPersoonia · 2022Article
- Genera of phytopathogenic fungi: GOPHY 4.Studies in mycology · 2022Article
- Phytophthora: an ancient, historic, biologically and structurally cohesive and evolutionarily successful generic concept in need of preservation.IMA fungus · 2022Article
- Variance of allele balance calculated from low coverage sequencing data infers departure from a diploid state.BMC bioinformatics · 2022Article
- Review
- A Comprehensive Assessment of the Secretome Responsible for Host Adaptation of the Legume Root PathogenJournal of fungi (Basel, Switzerland) · 2022Article
- "Core" RxLR effectors in phytopathogenic oomycetes: A promising way to breeding for durable resistance in plants?Virulence · 2021Article
- Article
- Predicting Lifestyle from Positive Selection Data and Genome Properties in Oomycetes.Pathogens (Basel, Switzerland) · 2021Article
- Genome of the destructive oomycete Phytophthora cinnamomi provides insights into its pathogenicity and adaptive potential.BMC genomics · 2021Article
- AFLAP: assembly-free linkage analysis pipeline using k-mers from genome sequencing data.Genome biology · 2021Article
- Fantastic Downy Mildew Pathogens and How to Find Them: Advances in Detection and Diagnostics.Plants (Basel, Switzerland) · 2021Review
- Evolutionary and genomic comparisons of hybrid uninucleate and nonhybrid Rhizoctonia fungi.Communications biology · 2021Article
- Uncovering the Role of Metabolism in Oomycete-Host Interactions Using Genome-Scale Metabolic Models.Frontiers in microbiology · 2021Review
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
Lettuce downy mildew caused by Bremia lactucae is the most important disease of lettuce globally. This oomycete is highly variable and rapidly overcomes resistance genes and fungicides. The use of multiple read types results in a high-quality, near-chromosome-scale, consensus assembly. Flow cytometry plus resequencing of 30 field isolates, 37 sexual offspring, and 19 asexual derivatives from single multinucleate sporangia demonstrates a high incidence of heterokaryosis in B. lactucae. Heterokaryosis has phenotypic consequences on fitness that may include an increased sporulation rate and qualitative differences in virulence. Therefore, selection should be considered as acting on a population of nuclei within coenocytic mycelia. This provides evolutionary flexibility to the pathogen enabling rapid adaptation to different repertoires of host resistance genes and other challenges. The advantages of asexual persistence of heterokaryons may have been one of the drivers of selection that resulted in the loss of uninucleate zoospores in multiple downy mildews.
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