ArticleNature communications2019
NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 65 citations in OpenAlex.
- The GUN1-NAC103 axis-mediated plastid signaling sustains root growth under plastid translation stress.The New phytologist · 2026Article
- Review
- Turning over a green leaf: integrating light signals toward chloroplast establishment.Plant physiology · 2026Review
- Functional conservation and diversity of phytochrome B and its potential applications in crop improvement.Plant communications · 2026Review
- Twenty-five years of photobodies: formation, composition, and the 2-compartment logic of phytochrome B signaling.Plant physiology · 2026Review
- Mechanisms underlying green flower formation.Horticulture research · 2026Article
- Advancements in photosynthetic efficiency: Pathways, regulation, and biotechnological applications for enhancing crop productivity.Plant signaling & behavior · 2025Review
- Light-regulated dual-targeting of NUCLEAR CONTROL OF PEP ACTIVITY establishes photomorphogenesis via interorganellar communication.Plant physiology · 2025Article
- Metabolism in Sync: The Circadian Clock, a Central Hub for Light-Driven Chloroplastic and Mitochondrial Entrainment.Plants (Basel, Switzerland) · 2025Review
- A PPR Protein RFCD1 Affects Chloroplast Gene Expression and Chloroplast Development inPlants (Basel, Switzerland) · 2025Article
- Cloning and high temperature tolerance analysis of the thermal response related geneFrontiers in plant science · 2025Article
- GhCTSF1, a short PPR protein with a conserved role in chloroplast development and photosynthesis, participates in intron splicing of rpoC1 and ycf3-2 transcripts in cotton.Plant communications · 2024Article
- What is going on inside of phytochrome B photobodies?The Plant cell · 2024Review
- Distinguishing individual photobodies using Oligopaints reveals thermo-sensitive and -insensitive phytochrome B condensation at distinct subnuclear locations.Nature communications · 2024Article
- Photobody formation spatially segregates two opposing phytochrome B signaling actions of PIF5 degradation and stabilization.Nature communications · 2024Article
- Regulation of chloroplast biogenesis, development, and signaling by endogenous and exogenous cues.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Characterization of Thermoresponsive Photobody Dynamics.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Chloroplast gene expression: Recent advances and perspectives.Plant communications · 2023Review
- The Role of Light Quality in Regulating Early Seedling Development.Plants (Basel, Switzerland) · 2023Review
- Phytochrome B photobodies are comprised of phytochrome B and its primary and secondary interacting proteins.Nature communications · 2023Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Phytochromes initiate chloroplast biogenesis by activating genes encoding the photosynthetic apparatus, including photosynthesis-associated plastid-encoded genes (PhAPGs). PhAPGs are transcribed by a bacterial-type RNA polymerase (PEP), but how phytochromes in the nucleus activate chloroplast gene expression remains enigmatic. We report here a forward genetic screen in Arabidopsis that identified NUCLEAR CONTROL OF PEP ACTIVITY (NCP) as a necessary component of phytochrome signaling for PhAPG activation. NCP is dual-targeted to plastids and the nucleus. While nuclear NCP mediates the degradation of two repressors of chloroplast biogenesis, PIF1 and PIF3, NCP in plastids promotes the assembly of the PEP complex for PhAPG transcription. NCP and its paralog RCB are non-catalytic thioredoxin-like proteins that diverged in seed plants to adopt nonredundant functions in phytochrome signaling. These results support a model in which phytochromes control PhAPG expression through light-dependent double nuclear and plastidial switches that are linked by evolutionarily conserved and dual-localized regulatory proteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.