Evidence map›Paper›PMID 31201277›Full record

ArticleApplied and environmental microbiology2019

A New Suite of Allelic-Exchange Vectors for the Scarless Modification of Proteobacterial Genomes.

Jacob E Lazarus, Alyson R Warr, Carole J Kuehl, Rachel T Giorgio, Brigid M Davis, Matthew K Waldor

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jacob E LazarusDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Alyson R WarrDepartment of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.
Carole J KuehlDepartment of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.
Rachel T GiorgioDepartment of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.
Brigid M DavisDepartment of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.
Matthew K WaldorDepartment of Microbiology, Harvard Medical School, Boston, Massachusetts, USA MWALDOR@research.bwh.harvard.edu.
Brigham and Women's Hospital · USHarvard University · USMassachusetts General Hospital · US

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Vibrio cholerae intestinal colonization and vaccine developmentR01AI042347 · NIAID · TUFTS UNIVERSITY BOSTON · PI WALDOR, MATTHEW K · 1998 to 2025
$7.3M
Bacteriology PhD Training ProgramT32AI132120 · NIAID · HARVARD MEDICAL SCHOOL · PI RUDNER, DAVID Z · 2017 to 2021
$1.7M
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI042347NIAID NIH HHS T32 AI007061NIAID NIH HHS T32 AI132120
6 · The paper itself

Abstract

Despite the advent of new techniques for genetic engineering of bacteria, allelic exchange through homologous recombination remains an important tool for genetic analysis. Currently,

Indexed as

Genome, BacterialAllelesAnti-Bacterial Agentsbeta-LactamsGenetic VectorsMicrobial Sensitivity TestsPlasmidsProteobacteriaAnti-Bacterial Agentsbeta-Lactamsallelic exchangeAmilCP geneampCampDantibiotic resistancebeta-lactamasesacBSerratia marcescenstoxin-antitoxintype VI toxin

Identifiers

PMID31201277
PMCPMC6677854
OpenAlexW2950945753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.