Evidence map›Paper›PMID 31201271›Full record

ArticleThe Journal of biological chemistry2019

FRET-based sensor for CaMKII activity (FRESCA): A useful tool for assessing CaMKII activity in response to Ca

Goli Ardestani, Megan C West, Thomas J Maresca, Rafael A Fissore, Margaret M Stratton

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases.Chembiochem : a European journal of chemical biology · 2026
    Review
  3. Article
  4. Sensitive and Selective Next-Generation FRET-based PKA Biosensors.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. CaMKII as a Therapeutic Target in Cardiovascular Disease.Annual review of pharmacology and toxicology · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Characterization of CaMKIIα holoenzyme stability.Protein science : a publication of the Protein Society · 2020
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Goli ArdestaniDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts 01003.
Megan C WestDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 01003.
Thomas J MarescaDepartment of Biology, University of Massachusetts, Amherst, Massachusetts 01003.
Rafael A FissoreDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts 01003.
Margaret M StrattonDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 01003 mstratton@biochem.umass.edu.ORCID 0000-0003-2686-9022
University of Massachusetts Amherst · US

Funding

Mechano-molecular regulation of kinetochore functionR01GM107026 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI MARESCA, THOMAS JOSEPH · 2013 to 2022
$2.7M
Regulation of the functional expression of the TRPM7 chanzyme essential for Mg2+ homeostasis in mouse oocytes and cleaving embryos to improve assisted reproductive technologies and modulate fertilityR01HD092499 · NICHD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Rafael Antonio Fissore · 2018 to 2026
$2.0M
CaMKII biophysics and its role in LTP: Undergraduate SupplementR01GM123157 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI STRATTON, MARGARET M · 2018 to 2022
$1.7M
LP3R-1 Regulation and Egg ActivationR01HD051872 · NICHD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI FISSORE, RAFAEL ANTONIO · 2007 to 2011
$1.3M
NICHD NIH HHS R01 HD051872NICHD NIH HHS R01 HD092499NIGMS NIH HHS R01 GM107026NIGMS NIH HHS R01 GM123157
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsBiosensing TechniquesCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2FertilizationFluorescence Resonance Energy TransferHEK293 CellsHumansIonomycinMiceOvumPhosphoinositide Phospholipase CCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2IonomycinPhosphoinositide Phospholipase CbiosensorCa2+/calmodulin-dependent protein kinase II (CaMKII)calcium imagingCamuifertilityfertilizationFRESCA (FRET-based sensor for CaMKII activity)phosphorylationreporter

Identifiers

PMID31201271
PMCPMC6682743
OpenAlexW2952032895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.