Evidence map›Paper›PMID 31201264›Full record

ArticleThe Journal of cell biology2019

Loss of nuclear envelope integrity? No probLEM-BAF has it covered.

Megan C King, C Patrick Lusk

Abstract readComment
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Increased expression of LAP2β eliminates nuclear membrane ruptures in nuclear lamin-deficient neurons and fibroblasts.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Megan C KingDepartment of Cell Biology, Yale School of Medicine, New Haven, CT megan.king@yale.edu.ORCID http://orcid.org/0000-0002-1688-2226
C Patrick LuskDepartment of Cell Biology, Yale School of Medicine, New Haven, CT.ORCID http://orcid.org/0000-0003-4703-0533

Funding

New Mechanisms of Heterotaxy and Congenital Heart Disease: Nucleoporins at CiliaR01HL124402 · NHLBI · YALE UNIVERSITY · PI KHOKHA, MUSTAFA K, LUSK, CHARLES PATRICK · 2015 to 2022
$5.5M
The mechanism of ESCRT-mediated surveillance of the nuclear envelope barrierR01GM105672 · NIGMS · YALE UNIVERSITY · PI LUSK, CHARLES PATRICK · 2013 to 2025
$4.6M
Remodeling of the structure and function of the nuclear lamina by LINC complex-dependent tensionR01GM129308 · NIGMS · YALE UNIVERSITY · PI KING, MEGAN C · 2018 to 2021
$1.3M
Leveraging cancer-specific defects in nuclear integrity to inform novel synthetic lethal strategiesR21CA231269 · NCI · YALE UNIVERSITY · PI KING, MEGAN C, LUSK, CHARLES PATRICK · 2019 to 2020
$401k
NCI NIH HHS R21 CA231269NHLBI NIH HHS R01 HL124402NIGMS NIH HHS R01 GM105672NIGMS NIH HHS R01 GM129308
6 · The paper itself

Abstract

Ruptures of the nuclear envelope can drive a catastrophic loss of nucleocytoplasmic compartmentalization. In this issue, Halfmann et al. (2019.

Indexed as

Cell NucleusNuclear Envelope

Identifiers

PMID31201264
PMCPMC6605804

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.