Evidence map›Paper›PMID 31201229›Full record

ArticlePediatrics2019

Mental Illness Among Youth With Chronic Physical Conditions.

John S Adams, Alyna T Chien, Lauren E Wisk

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
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  8. Trajectories of health-related quality of life in youth with chronic physical illness and their siblings.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  18. Associations between physical diseases and subsequent mental disorders: a longitudinal study in a population-based cohort.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

John S AdamsDepartment of Pediatrics, Cambridge Health Alliance, Cambridge, Massachusetts; josadams@challiance.org.
Alyna T ChienDepartment of Pediatrics, Harvard Medical School, Harvard University, Boston, Massachusetts; and.
Lauren E WiskDepartment of Pediatrics, Harvard Medical School, Harvard University, Boston, Massachusetts; and.
Boston Children's Hospital · USCambridge Health Alliance · USHarvard University · US

Funding

Mentored Career Development for Child and Family Centered Outcomes ResearchK12HS022986 · AHRQ · BOSTON CHILDREN'S HOSPITAL · PI FINKELSTEIN, JONATHAN A · 2014 to 2018
$3.8M
AHRQ HHS K12 HS022986
6 · The paper itself

Abstract

BACKGROUND AND

objectivesYouth with chronic physical conditions (CPCs) may be at greater risk for developing chronic mental health conditions (MHCs), and limitations in the ability to engage in developmentally appropriate activities may contribute to the risk of MHCs among youth with CPCs. We compared the risk of incident MHCs in youth with and without CPCs and explored whether activity limitations contribute to any such association.

methodsThe 2003-2014 Medical Expenditure Panel Survey provided a nationally representative cohort of 48 572 US youth aged 6 to 25 years. We calculated the 2-year cumulative incidence of MHCs overall and by baseline CPC status. Cox proportional hazard models were used to estimate the association between CPCs and incident MHCs, adjusting for sociodemographic characteristics. Stepwise models and the Sobel test evaluated activity limitations as a mediator of this relationship.

resultsThe 2-year cumulative incidence of MHCs was 7.8% overall, 11.5% in youth with CPCs (14.7% of sample), and 7.1% in those without. The adjusted risk of incident MHCs was 51% greater (adjusted hazard ratio 1.51; 95% confidence interval 1.30-1.74) in youth with CPCs compared with those without. Activity limitations mediated 13.5% of this relationship (

conclusionsThis nationally representative cohort study supports the hypotheses that youth with CPCs have increased risk for MHCs and that activity limitations may play a role in MHC development. Youth with CPCs may benefit from services to bolster their ability to participate in developmentally important activities and to detect and treat new onset MHCs.

Indexed as

AdolescentAdultChildChronic DiseaseComorbidityHumansIncidenceMental DisordersProportional Hazards ModelsRisk FactorsYoung Adult

Identifiers

PMID31201229
PMCPMC12930273
OpenAlexW2949657726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.