Evidence map›Paper›PMID 31201208›Full record

ArticleThe Journal of experimental medicine2019

KLRG1 and NKp46 discriminate subpopulations of human CD117

Maho Nagasawa, Balthasar A Heesters, Chantal M A Kradolfer, Lisette Krabbendam, Itziar Martinez-Gonzalez, Marjolein J W de Bruijn, Korneliusz Golebski, Rudi W Hendriks, Ralph Stadhouders, Hergen Spits and 1 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 117 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Human CD127 negative ILC2s show immunological memory.The Journal of experimental medicine · 2024
    Article
  12. Article
  13. CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy.Clinical reviews in allergy & immunology · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Programmed cell death-1 receptor-mediated regulation of TbetProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Maho NagasawaDepartment of Experimental Immunology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Balthasar A HeestersDepartment of Experimental Immunology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-2909-8481
Chantal M A KradolferDepartment of Experimental Immunology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Lisette KrabbendamDepartment of Experimental Immunology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Itziar Martinez-GonzalezDepartment of Experimental Immunology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Marjolein J W de BruijnDepartment of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands.
Korneliusz GolebskiDepartment of Experimental Immunology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Rudi W HendriksDepartment of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands.ORCID 0000-0003-2291-0382
Ralph StadhoudersDepartment of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands.ORCID 0000-0002-1060-5607
Hergen SpitsDepartment of Experimental Immunology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands hergen.spits@amc.uva.nl.ORCID 0000-0003-3269-8338
Suzanne M BalDepartment of Experimental Immunology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands s.m.bal@amc.nl.ORCID 0000-0002-3133-6450
Amsterdam University Medical Centers · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, human ILCs that express CD117 and CD127 but lack CRTH2 and NKp44 have been shown to contain precursors of ILC1, ILC2, and ILC3. However, these ILCs have not been extensively characterized. We performed an unbiased hierarchical stochastic neighbor embedding (HSNE) analysis of the phenotype of peripheral blood CD117

Indexed as

AnimalsBlood DonorsCell DifferentiationCell LineCytokinesEpigenesis, GeneticHumansImmunity, InnateKiller Cells, NaturalLectins, C-TypeMiceNatural Cytotoxicity Triggering Receptor 1Natural Cytotoxicity Triggering Receptor 2Palatine TonsilPhenotypeProto-Oncogene Proteins c-kitCytokinesKIT protein, humanKLRG1 protein, humanLectins, C-TypeNatural Cytotoxicity Triggering Receptor 1Natural Cytotoxicity Triggering Receptor 2NCR1 protein, humanNCR2 protein, humanprostaglandin D2 receptorProto-Oncogene Proteins c-kitReceptors, ImmunologicReceptors, Prostaglandin

Identifiers

PMID31201208
PMCPMC6683990
OpenAlexW2950984072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.