ArticleNeuron2019
Open Source Brain: A Collaborative Resource for Visualizing, Analyzing, Simulating, and Developing Standardized Models of Neurons and Circuits.
Article in Neuron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- BRAINCELL modelling platform for stochastic nanoscale organisation and dynamic extracellular signalling among neurons and glia.Nature communications · 2026Article
- Visualization and simulation of full-scale point-neuron circuits via the Neural Circuit Visualizer web platform.Scientific reports · 2026Article
- The neuroscience education readiness checklist for digital tools and methods.Frontiers in computational neuroscience · 2026Article
- Building on models-a perspective for computational neuroscience.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Self-organized and self-sustained ensemble activity patterns in simulation of mouse primary motor cortex.bioRxiv : the preprint server for biology · 2025Article
- Article
- Neuromorphic computing at scale.Nature · 2025Review
- NESTML: a generic modeling language and code generation tool for the simulation of spiking neural networks with advanced plasticity rules.Frontiers in neuroinformatics · 2025Article
- Large-Scale Mechanistic Models of Brain Circuits with Biophysically and Morphologically Detailed Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- A Visual Interface for Exploring Hypotheses About Neural Circuits.IEEE transactions on visualization and computer graphics · 2024Article
- Towards building a trustworthy pipeline integrating Neuroscience Gateway and Open Science Chain.Database : the journal of biological databases and curation · 2024Article
- Methods and considerations for estimating parameters in biophysically detailed neural models with simulation based inference.PLoS computational biology · 2024Article
- Computational modeling to study the impact of changes in Nav1.8 sodium channel on neuropathic pain.Frontiers in computational neuroscience · 2024Article
- Data-driven multiscale model of macaque auditory thalamocortical circuits reproduces in vivo dynamics.Cell reports · 2023Article
- Multiscale model of primary motor cortex circuits predicts in vivo cell-type-specific, behavioral state-dependent dynamics.Cell reports · 2023Article
- Methods and considerations for estimating parameters in biophysically detailed neural models with simulation based inference.bioRxiv : the preprint server for biology · 2023Article
- NeuroML-DB: Sharing and characterizing data-driven neuroscience models described in NeuroML.PLoS computational biology · 2023Article
- Learning the dynamics of realistic models of C. elegans nervous system with recurrent neural networks.Scientific reports · 2023Article
- Online interoperable resources for building hippocampal neuron models via the Hippocampus Hub.Frontiers in neuroinformatics · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Funding
Abstract
Computational models are powerful tools for exploring the properties of complex biological systems. In neuroscience, data-driven models of neural circuits that span multiple scales are increasingly being used to understand brain function in health and disease. But their adoption and reuse has been limited by the specialist knowledge required to evaluate and use them. To address this, we have developed Open Source Brain, a platform for sharing, viewing, analyzing, and simulating standardized models from different brain regions and species. Model structure and parameters can be automatically visualized and their dynamical properties explored through browser-based simulations. Infrastructure and tools for collaborative interaction, development, and testing are also provided. We demonstrate how existing components can be reused by constructing new models of inhibition-stabilized cortical networks that match recent experimental results. These features of Open Source Brain improve the accessibility, transparency, and reproducibility of models and facilitate their reuse by the wider community.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.