Evidence map›Paper›PMID 31201039›Full record

ArticleEpidemics2019

Phylogeography of rubella virus in Asia: Vaccination and demography shape synchronous outbreaks.

Brooke A Bozick, Colin J Worby, C Jessica E Metcalf

Open access · goldAbstract read
In one paragraph

Article in Epidemics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brooke A BozickDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, United States. Electronic address: bbozick@princeton.edu.
Colin J WorbyDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, United States.
C Jessica E MetcalfDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, United States.
Princeton University · US

Funding

Scientific and Technical Computing CoreP2CHD047879 · NICHD · PRINCETON UNIVERSITY · PI SALGANIK, MATTHEW J. · 2014 to 2018
$2.0M
NICHD NIH HHS P2C HD047879
6 · The paper itself

Abstract

Rubella virus causes mild disease in children but for women in the early stages of pregnancy, it can cause spontaneous abortion, congenital rubella syndrome (CRS) and associated birth defects. Despite the availability of an effective vaccine, rubella virus continues to circulate endemically in several regions of the world. This is particularly true in East and Southeast (E/SE) Asia, where control efforts vary widely among countries that are well connected through travel and immigration. It is therefore important to understand how the regional persistence of rubella is affected both by dynamics occurring across countries and susceptibility within countries. Here, we use genetic and epidemiological data from countries in E/SE Asia to explore the phylogeography of rubella virus in this region. Our results underline that metapopulation dynamics are key for rubella persistence and highlight the source-sink population structure of the region. We identify countries that contribute to the regional metapopulation network and link epidemic dynamics to susceptibility profiles within each country. Our results indicate that human movement plays an important role in driving epidemic dynamics in E/SE Asia.

Indexed as

Rubella virusAdultAsia, SoutheasternChildDemographyDisease OutbreaksFemaleHumansMalePhylogeographyRubellaTravelVaccinationEpidemic dynamicsHuman movementMetapopulationPhylogeographyRubella virus

Identifiers

PMID31201039
PMCPMC6731519
OpenAlexW2946958881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.