Evidence map›Paper›PMID 31200781›Full record

ArticleCritical care (London, England)2019

Thinking forward: promising but unproven ideas for future intensive care.

John J Marini, Daniel DeBacker, Luciano Gattinoni, Can Ince, Ignacio Martin-Loeches, Pierre Singer, Mervyn Singer, Martin Westphal, Jean-Louis Vincent

Abstract read
In one paragraph

Article in Critical care (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

John J MariniRegions Hospital, University of Minnesota, MS11203B, 640 Jackson Street, Minneapolis/St.Paul, MN, 55101, USA. marin002@umn.edu.
Daniel DeBackerCHIREC Hospitals, Brussels, Belgium.
Luciano GattinoniUniversity of Gottingen, Gottingen, Germany.
Can InceErasmus University Medical Center, Rotterdam, Netherlands.
Ignacio Martin-LoechesSt. James Hospital, Dublin, Ireland.
Pierre SingerRabin Medical Center, Tel Aviv, Israel.
Mervyn SingerUniversity College London Medical School, London, UK.
Martin WestphalUniversity of Muenster, Muenster, Germany.
Jean-Louis VincentErasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium.

Funding

FreseniusKabi None
6 · The paper itself

Abstract

Progress toward determining the true worth of ongoing practices or value of recent innovations can be glacially slow when we insist on following the conventional stepwise scientific pathway. Moreover, a widely accepted but flawed conceptual paradigm often proves difficult to challenge, modify or reject. Yet, most experienced clinicians, educators and clinical scientists privately entertain untested ideas about how care could or should be improved, even if the supporting evidence base is currently thin or non-existent. This symposium encouraged experts to share such intriguing but unproven concepts, each based upon what the speaker considered a logical but unproven rationale. Such free interchange invited dialog that pointed toward new or neglected lines of research needed to improve care of the critically ill. In this summary of those presentations, a brief background outlines the rationale for each novel and deliberately provocative unconfirmed idea endorsed by the presenter.

Indexed as

ForecastingCritical CareCritical IllnessHumansAntibiotic overuseAscorbic acidInnovationLactateLithiumNanotechnologyNutritional supportParadigmPost-intensive care syndromeSubcellular microscopy

Identifiers

PMID31200781
PMCPMC6570630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.