Evidence map›Paper›PMID 31200717›Full record

ArticleBMC veterinary research2019

Experimental infection of Korean native goats (Capra aegagrus hircus) with bovine viral diarrhea virus 1b.

Jae-Ku Oem, Du-Gyeong Han, Kyoung-Seong Choi

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Jae-Ku OemCollege of Veterinary Medicine, Chonbuk National University, Iksan, 54596, Republic of Korea.
Du-Gyeong HanDivision of Bacterial Disease Research, Center for Infectious Disease Research, Korea National Institute of Health, Korea Centers for Disease Control and Prevention, Osong, 28159, Republic of Korea.
Kyoung-Seong ChoiDepartment of Animal Science and Biotechnology, College of Ecology and Environmental Science, Kyungpook National University, Sangju, 37224, Republic of Korea. kschoi3@knu.ac.kr.ORCID http://orcid.org/0000-0002-2271-5360
Jeonbuk National University · KRKorea National Institute of Health · KRKyungpook National University · KR

Funding

National Research Foundation of Korea (KR) 2018R1D1A1B07048271
6 · The paper itself

Abstract

backgroundBovine viral diarrhea virus (BVDV) infects various ungulates and causes reproductive failure in infected goats. BVDV has been detected among goats in the Republic of Korea, but the route of transmission remains unclear. Here, we aimed to investigate whether BVDV-1b circulating among Korean cattle can be transmitted to Korean native goats (Capra aegagrus hircus) and characterize the outcomes of BVDV infection in these goats.

resultsFour goats were inoculated intranasally with the Korean noncytopathic (ncp) BVDV-1b strain. Two goats exhibited clinical signs of illness, including coughing and nasal discharge. Nasal swabs and blood were collected to screen for viral RNA and BVDV antibodies. Using the 5'-untranslated region (UTR), viral RNA was detected in the nasal swabs of two goats (Goat 1 and 3) on 12 day post-inoculation (dpi) and in the blood sample of one goat (Goat 1) on 7 and 19 dpi. Using the N-terminal protease (N

conclusionsOur results indicate that changes in the nucleotide sequence are associated with the establishment of BVDV infection in Korean native goats; these changes may be owing to a process required for the establishment of infection in a new host reservoir. Broadly, these findings highlight the importance of BVDV surveillance in ungulates other than cattle.

Indexed as

5' Untranslated RegionsAnimalsAntibodies, ViralDiarrhea Virus 1, Bovine ViralEnzyme-Linked Immunosorbent AssayFemaleGoat DiseasesGoatsNasal MucosaPestivirus InfectionsRepublic of KoreaRNA, ViralSequence Analysis, RNA5' Untranslated RegionsAntibodies, ViralRNA, Viral5′-untranslated regionBovine viral diarrhea virusKorean native goatNoncytopathicN-terminal protease region

Identifiers

PMID31200717
PMCPMC6570889
OpenAlexW2951423648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.