Evidence map›Paper›PMID 31200652›Full record

ArticleBMC infectious diseases2019

A rare case of an HIV-seronegative AIDS patient with Pneumocystis jirovecii pneumonia.

Shuangquan Yan, Jing Huang, Qiaofei Zheng, Hongguo Zhu, Zhuolin Gao, Jiaxi Feng, Youzu Xu

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Epidemiology of Kaposi's sarcoma in Zambia, 2007 - 2014.Malawi medical journal : the journal of Medical Association of Malawi · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shuangquan YanDivision of Respiratory Medicine, Taizhou Enze Medical Center Enze Hospital, No. 1 East TongYang Load, Luqiao District, Taizhou, Zhejiang, 318000, People's Republic of China.
Jing HuangDivision of Respiratory Medicine, Taizhou Enze Medical Center Enze Hospital, No. 1 East TongYang Load, Luqiao District, Taizhou, Zhejiang, 318000, People's Republic of China.
Qiaofei ZhengDivision of Clinic Laboratory, Taizhou Enze Medical Center TaiZhou Hospital, Taizhou, 318000, Zhejiang, China.
Hongguo ZhuDivision of Clinic Laboratory, Taizhou Enze Medical Center Enze Hospital, Taizhou, 318000, Zhejiang, China.
Zhuolin GaoDivision of Respiratory Medicine, Taizhou Enze Medical Center Enze Hospital, No. 1 East TongYang Load, Luqiao District, Taizhou, Zhejiang, 318000, People's Republic of China.
Jiaxi FengDivision of Respiratory Medicine, Taizhou Enze Medical Center Enze Hospital, No. 1 East TongYang Load, Luqiao District, Taizhou, Zhejiang, 318000, People's Republic of China.
Youzu XuDivision of Respiratory Medicine, Taizhou Enze Medical Center Enze Hospital, No. 1 East TongYang Load, Luqiao District, Taizhou, Zhejiang, 318000, People's Republic of China. xuyz@enzemed.com.
Wenzhou Medical University · CNZhejiang Taizhou Hospital · CN

Funding

technology bureau of TaiZhou, Zhejiang Province of China 1701KY52
6 · The paper itself

Abstract

backgroundAs technology progresses, several highly sensitive human immunodeficiency virus (HIV) screening kits are being researched and developed to quickly and efficiently identify serum HIV antibodies within the non-window period. In individuals who are HIV-seronegative, HIV infections that are not within a window period are rare. In such cases, all antibody detection methods will fail, and misdiagnosing these patients will have catastrophic consequences. CASE PRESENTATION: A 22-year-old male Chinese patient with diffuse exudative lesions in both lungs and initial symptoms of cough and dyspnoea was diagnosed with Pneumocystis jirovecii pneumonia (PJP) by aetiological examination, and the patient's plasma CD4

conclusionThis is the second reported case in China of an HIV-seronegative AIDS patient. Such cases are also rare worldwide. Although HIV-seronegative HIV infections are rare, AIDS should be considered in immunodeficient patients with opportunistic infections, even if the test results are HIV-seronegative. Plasma HIV RNA testing is important for such patients.

Indexed as

Acquired Immunodeficiency SyndromeAIDS-Related Opportunistic InfectionsAnti-Bacterial AgentsAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountHumansMalePneumocystis cariniiPneumonia, PneumocystisRNA, ViralTreatment OutcomeYoung AdultAnti-Bacterial AgentsRNA, ViralAIDS patientsHIV-seronegativePneumocystis jirovecii pneumonia

Identifiers

PMID31200652
PMCPMC6570926
OpenAlexW2949930022

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.