Evidence map›Paper›PMID 31200649›Full record

Trial reportBMC geriatrics2019

Effects of intermittent hypoxia-hyperoxia on mobility and perceived health in geriatric patients performing a multimodal training intervention: a randomized controlled trial.

Ulrike Bayer, Rudolf Likar, Georg Pinter, Haro Stettner, Susanne Demschar, Brigitte Trummer, Stefan Neuwersch, Oleg Glazachev, Martin Burtscher

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Ulrike BayerDepartment of Geriatrics, Klinikum Klagenfurt, Kraßniggstraße 2, 9020, Klagenfurt am Wörthersee, Austria.
Rudolf LikarDepartment of Anesthesiology and Intensive Care Medicine, Klinikum Klagenfurt, Feschnigstr. 11, 9020, Klagenfurt, Austria.
Georg PinterDepartment of Geriatrics, Klinikum Klagenfurt, Kraßniggstraße 2, 9020, Klagenfurt am Wörthersee, Austria.
Haro StettnerDepartment of Statistics, Alpen-Adria University Klagenfurt, Universitätsstraße 65-67, 9020, Klagenfurt, Austria.
Susanne DemscharDepartment of Anesthesiology and Intensive Care Medicine, Klinikum Klagenfurt, Feschnigstr. 11, 9020, Klagenfurt, Austria.
Brigitte TrummerDepartment of Anesthesiology and Intensive Care Medicine, Klinikum Klagenfurt, Feschnigstr. 11, 9020, Klagenfurt, Austria.
Stefan NeuwerschDepartment of Anesthesiology and Intensive Care Medicine, Klinikum Klagenfurt, Feschnigstr. 11, 9020, Klagenfurt, Austria.
Oleg GlazachevScience and Technology Park for Biomedicine, I.M, Sechenov First Moscow State Medical University, Trubetskaya Str. 8-2, 119991, Moscow, Russia.
Martin BurtscherDepartment of Sport Science, Medical Section, University of Innsbruck, Fürstenweg 185, 6020, Innsbruck, Austria. martin.burtscher@uibk.ac.at.ORCID 0000-0002-5232-3632
Klinikum Klagenfurt · ATInnsbruck Medical University · ATSechenov University · RUUniversity of Klagenfurt · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdditional benefits of passive exposures to intermittent hypoxia and hyperoxia on cognitive performance and functional exercise capacity have been demonstrated in geriatric patients who performed a multimodal training program. The main goal of the present study was to evaluate effects of adding intermittent hypoxic-hyperoxic training (IHHT) to a multimodal training intervention (MTI) on mobility and perceived health in old individuals at a Geriatric Day Hospital.

methodsThirty-four patients between 64 and 92 years participated in the double blind, randomized and controlled clinical trial. The elderly patients attended in a 5-7 weeks lasting MTI (strength, endurance, balance, reaction, flexibility, coordination, and cognitive exercises) and performed IHHT (breathing 10-14% oxygen for 4-7 min followed by 2-4 min 30-40% oxygen) in the Hypoxic Group (HG) or placebo treatment with ambient air in the Normoxic Group (NG) in parallel. Before and after all treatments, mobility was assessed by the Tinetti Mobility Test (TMT), the Timed-Up-and-Go Test (TUG) and Barthel-Index, while perceived health was assessed by one part of the EQ-5D Test, the EQ visual analogue scale (EQ VAS).

resultsAfter the MTI plus IHHT or normoxia sessions, results of the TMT, TUG, Barthel Index and EQ-VAS revealed no significant difference between HG and NG (+ 14.9% vs + 15.4%, p = 0.25; - 21% vs - 26.3%, p = 0.51; + 4.2% vs + 3.6%, p = 0.56; + 37.9% vs + 33.9%, p = 0.24;).

conclusionsIHHT added to MTI did not elicit additional improvements in perceived health and mobility compared to MTI alone.

Indexed as

Health StatusAgedAged, 80 and overDouble-Blind MethodExerciseExercise TherapyExercise ToleranceFemaleHumansHyperoxiaHypoxiaMaleMiddle AgedPostural BalanceRange of Motion, ArticularTime and Motion StudiesElderlyHypoxiaInterventionMultimodal trainingPerceived health

Identifiers

PMID31200649
PMCPMC6570826
OpenAlexW2952204758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.