Evidence map›Paper›PMID 31200588›Full record

ArticleCancers2019

Efficacy and Toxicity of Weekly Carboplatin and Paclitaxel as Induction or Palliative Treatment in Advanced Esophageal Cancer Patients.

Femke M de Man, Ruben A G van Eerden, Esther Oomen-de Hoop, Joris N Veraart, Nadia van Doorn, Leni van Doorn, Ate van der Gaast, Ron H J Mathijssen

Abstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Can Cisplatin Therapy Be Improved? Pathways That Can Be Targeted.International journal of molecular sciences · 2022
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Femke M de ManDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. f.deman@erasmusmc.nl.
Ruben A G van EerdenDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. r.vaneerden@erasmusmc.nl.
Esther Oomen-de HoopDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. e.oomen-dehoop@erasmusmc.nl.
Joris N VeraartDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. j.veraart@erasmusmc.nl.
Nadia van DoornDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. n.vandoorn@erasmusmc.nl.
Leni van DoornDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. l.vandoorn@erasmusmc.nl.
Ate van der GaastDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. a.vandergaast@erasmusmc.nl.
Ron H J MathijssenDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. a.mathijssen@erasmusmc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many patients have advanced esophageal cancer at diagnosis. However, the most optimal treatment has not been identified. Therefore, we evaluated a weekly regimen of carboplatin (area under the curve (AUC)) of 4 and paclitaxel at 100 mg/m

Indexed as

efficacyesophageal cancerinduction treatmentpalliative treatmenttoxicity

Identifiers

PMID31200588
PMCPMC6627268

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.