Evidence map›Paper›PMID 31200538›Full record

ReviewMolecules (Basel, Switzerland)2019

Porous Silicon-Based Aptasensors: The Next Generation of Label-Free Devices for Health Monitoring.

Monica Terracciano, Ilaria Rea, Nicola Borbone, Rosalba Moretta, Giorgia Oliviero, Gennaro Piccialli, Luca De Stefano

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Monica TerraccianoInstitute for Microelectronics and Microsystems, Via P. Castellino 111, 80131 Naples, Italy. monica.terracciano@na.imm.cnr.it.ORCID 0000-0001-6367-2419
Ilaria ReaInstitute for Microelectronics and Microsystems, Via P. Castellino 111, 80131 Naples, Italy. ilaria.rea@na.imm.cnr.it.ORCID 0000-0003-0568-9911
Nicola BorboneDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy. nicola.borbone@unina.it.ORCID 0000-0003-0216-9814
Rosalba MorettaInstitute for Microelectronics and Microsystems, Via P. Castellino 111, 80131 Naples, Italy. rosalba.moretta@na.imm.cnr.it.
Giorgia OlivieroDepartment of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy. golivier@unina.it.ORCID 0000-0003-0765-2127
Gennaro PiccialliDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy. picciall@unina.it.
Luca De StefanoInstitute for Microelectronics and Microsystems, Via P. Castellino 111, 80131 Naples, Italy. luca.destefano@na.imm.cnr.it.ORCID 0000-0002-9442-4175

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aptamers are artificial nucleic acid ligands identified and obtained from combinatorial libraries of synthetic nucleic acids through the in vitro process SELEX (systematic evolution of ligands by exponential enrichment). Aptamers are able to bind an ample range of non-nucleic acid targets with great specificity and affinity. Devices based on aptamers as bio-recognition elements open up a new generation of biosensors called aptasensors. This review focuses on some recent achievements in the design of advanced label-free optical aptasensors using porous silicon (PSi) as a transducer surface for the detection of pathogenic microorganisms and diagnostic molecules with high sensitivity, reliability and low limit of detection (LoD).

Indexed as

Aptamers, NucleotideBiosensing TechniquesPorosityReproducibility of ResultsSELEX Aptamer TechniqueSiliconAptamers, NucleotideSiliconaptameraptasensoroptical label free-sensingporous siliconsurface modification

Identifiers

PMID31200538
PMCPMC6630495

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.