Evidence map›Paper›PMID 31200517›Full record

ReviewInternational journal of molecular sciences2019

Genome Editing in Agriculture: Technical and Practical Considerations.

Julia Jansing, Andreas Schiermeyer, Stefan Schillberg, Rainer Fischer, Luisa Bortesi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. In Vivo Rapid Investigation of CRISPR-Based Base Editing Components inInternational journal of molecular sciences · 2022
    Article
  8. Review
  9. To become more sustainable organic agriculture needs genome editing technology.Frontiers in bioengineering and biotechnology · 2022
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. PeerJ · 2021
    Article
  16. Review
  17. Article
  18. Perspectives for Buck Kids in Dairy Goat Farming.Frontiers in veterinary science · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia JansingAachen-Maastricht Institute for Biobased Materials (AMIBM), Maastricht University, Brightlands Chemelot Campus, Urmonderbaan 22, 6167 RD Geleen, The Netherlands. julia.jansing@maastrichtuniversity.nl.
Andreas SchiermeyerFraunhofer Institute for Molecular Biology and Applied Ecology IME, Forckenbeckstrasse 6, 52074 Aachen, Germany. andreas.schiermeyer@ime.fraunhofer.de.ORCID 0000-0002-2057-4111
Stefan SchillbergFraunhofer Institute for Molecular Biology and Applied Ecology IME, Forckenbeckstrasse 6, 52074 Aachen, Germany. stefan.schillberg@ime.fraunhofer.de.ORCID 0000-0002-1896-4575
Rainer FischerIndiana Biosciences Research Institute (IBRI), 1345 W. 16th St. Suite 300, Indianapolis, IN 46202, USA. rfischer@indianabiosciences.org.
Luisa BortesiAachen-Maastricht Institute for Biobased Materials (AMIBM), Maastricht University, Brightlands Chemelot Campus, Urmonderbaan 22, 6167 RD Geleen, The Netherlands. luisa.bortesi@maastrichtuniversity.nl.

Funding

Province of Limburg SAS-2014-00828
6 · The paper itself

Abstract

The advent of precise genome-editing tools has revolutionized the way we create new plant varieties. Three groups of tools are now available, classified according to their mechanism of action: Programmable sequence-specific nucleases, base-editing enzymes, and oligonucleotides. The corresponding techniques not only lead to different outcomes, but also have implications for the public acceptance and regulatory approval of genome-edited plants. Despite the high efficiency and precision of the tools, there are still major bottlenecks in the generation of new and improved varieties, including the efficient delivery of the genome-editing reagents, the selection of desired events, and the regeneration of intact plants. In this review, we evaluate current delivery and regeneration methods, discuss their suitability for important crop species, and consider the practical aspects of applying the different genome-editing techniques in agriculture.

Indexed as

Gene EditingPlant Breedingbase editorsoligonucleotide-directed mutagenesisprecision breedingprogrammable nucleasessequence-specific nucleases

Identifiers

PMID31200517
PMCPMC6627516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.