Evidence map›Paper›PMID 31200439›Full record

ArticleCancers2019

Uveal Melanoma: A European Network to Face the Many Challenges of a Rare Cancer.

Sophie Piperno-Neumann, Jose Maria Piulats, Matthias Goebeler, Iain Galloway, Iwona Lugowska, Jürgen C Becker, Pia Vihinen, Joachim Van Calster, Theodora Hadjistilianou, Rui Proença and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Uveal Melanoma: Changing Paradigms of Treatment.Ocular oncology and pathology · 2026
    Review
  4. Article
  5. Article
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  7. Review
  8. Review
  9. Article
  10. Article
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  13. Article
  14. Uveal Melanoma.Cancers · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 9 countries.

Sophie Piperno-NeumannDepartment of Medical Oncology, Institut Curie, 75005 Paris, France. sophie.piperno-neumann@curie.fr.
Jose Maria PiulatsDepartment of Medical Oncology, Catalan Cancer Institute, IDIBELL, CIBERONC, Hospitalet de Llobregat, 08908 Barcelona, Spain. jmpiulats@iconcologia.net.
Matthias GoebelerDepartment of Dermatology, University Hospital Würzburg, 97080 Würzburg, Germany. Goebeler_M1@ukw.de.
Iain GallowayEuropean Patient Advocacy Group: Melanoma Patient Network Europe & OcuMel, Birmingham B13 8ET, UK. iain@idcapture.co.uk.
Iwona LugowskaDepartment of Melanoma, Maria Skłodowska Curie Institute-Oncology Centre, 02-034 Warsaw, Poland. Iwona.Lugowska@coi.pl.
Jürgen C BeckerTranslational Skin Cancer Research, University of Essen-Duisburg, German Cancer Consortium (DKTK), 47057 Duisburg, Germany. j.becker@dkfz.de.ORCID 0000-0001-9183-653X
Pia VihinenDepartment of Oncology and FICAN West Cancer Center, Turku University Hospital, 20521 Turku, Finland. Pia.Vihinen@tyks.fi.ORCID 0000-0003-1763-5363
Joachim Van CalsterDepartment of Ophthalmology, UZ Leuven, 3000 Leuven, Belgium. joachim.vancalster@uzleuven.be.ORCID 0000-0001-7466-8394
Theodora HadjistilianouDepartment of Ophthalmology, Università degli Studi di Siena UNISI, 53100 Siena, Italy. hadjistilian@unisi.it.
Rui ProençaOnco-Ophthalmology National Reference Centre, CHUC, 3075 Coimbra, Portugal. rdproenca@gmail.com.ORCID 0000-0003-3459-8664
Jose Maria CaminalDepartment of Ophthalmololgy, Bellvitge University Hospital, L'Hospitalet de Llobregat, 08907 Barcelona, Spain. jmcaminal@bellvitgehospital.cat.
Muriel RogasikEURACAn coordination team, Centre Léon Bérard, 69008 Lyon, France. muriel.rogasik@lyon.unicancer.fr.
Jean-Yves BlayEURACAN network coordinator, Department of Medical Oncology, Centre Léon Bérard, Université Claude Bernard Lyon 1, 69100 Villeurbanne, France. jean-yves.blay@lyon.unicancer.fr.ORCID 0000-0001-7190-120X
Ellen KapiteijnDepartment of Medical Oncology, LUMC, 2333 ZA Leiden, the Netherlands. H.W.Kapiteijn@lumc.nl.
Bellvitge University Hospital · ESCentre Léon Bérard · FRDeutschen Konsortium für Translationale Krebsforschung · DEInstitut Curie · FRInstitut d'Investigació Biomédica de Bellvitge · ESLeiden University Medical Center · NLThe Maria Sklodowska-Curie National Research Institute of Oncology · PLThe Patients Association · GBTurku University Hospital · FIUniversitair Ziekenhuis Leuven · BEUniversitätsklinikum Würzburg · DEUniversité Claude Bernard Lyon 1 · FRUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uveal melanoma (UM) is the most frequent primary ocular cancer in adults, accounting for 5% of all melanomas. Despite effective treatments for the primary tumour, up to 50% of UM patients will develop metastasis, leading to a very poor prognosis and a median overall survival of 6 to 12 months, with no major improvements in the last 30 years. There is no standard oncological treatment available for metastatic UM patients, and BRAF/MEK and immune checkpoint inhibitors show disappointing results when compared to cutaneous melanoma (CM). Recent advances in biology, however, identified specific gene and chromosome alterations, potentially permitting an actively tailored surveillance strategy, and dedicated clinical studies. Being a rare cancer, UM patients have to overcome issues such as identifying referral centres, having access to information, and partnering with oncologists for specific management strategies and research priorities. Here, we describe how the EUropean Rare Adult solid CAacer Network (EURACAN) will help in addressing these challenges and accelerating international collaborations to enhance the development of innovative treatments in UM.

Indexed as

European Reference Networkrare canceruveal melanoma

Identifiers

PMID31200439
PMCPMC6628377
OpenAlexW2949799754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.