Evidence map›Paper›PMID 31199666›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

The S52F FOXF1 Mutation Inhibits STAT3 Signaling and Causes Alveolar Capillary Dysplasia.

Arun Pradhan, Andrew Dunn, Vladimir Ustiyan, Craig Bolte, Guolun Wang, Jeffrey A Whitsett, Yufang Zhang, Alexey Porollo, Yueh-Chiang Hu, Rui Xiao and 5 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 86 citations in OpenAlex.

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  10. CRISPR-Cas9 Genome Editing Allows Generation of the Mouse Lung in a Rat.American journal of respiratory and critical care medicine · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Arun PradhanDepartment of Pediatrics.
Andrew DunnDepartment of Pediatrics.
Vladimir UstiyanDepartment of Pediatrics.
Craig BolteDepartment of Pediatrics.
Guolun WangDepartment of Pediatrics.
Jeffrey A WhitsettDepartment of Pediatrics.
Yufang ZhangDepartment of Pediatrics.
Alexey PorolloDepartment of Pediatrics.
Yueh-Chiang HuDepartment of Pediatrics.
Rui XiaoBaylor Genetics, Houston, Texas; and.
Przemyslaw SzafranskiDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Donglu ShiThe Materials Science and Engineering Program, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio.
Pawel StankiewiczBaylor Genetics, Houston, Texas; and.
Tanya V KalinDepartment of Pediatrics.
Vladimir V KalinichenkoDepartment of Pediatrics.
Baylor College of Medicine · USPulmonary Associates · USUniversity of Cincinnati · USAutoimmune Technologies (United States) · USCenter for Neuroscience and Regenerative Medicine · USCincinnati Children's Hospital Medical Center · US

Funding

Fox Transcription Factors in Development of Pulmonary CapillariesR01HL084151 · NHLBI · UNIVERSITY OF CHICAGO · PI KALINICHENKO, VLADIMIR · 2006 to 2018
$4.9M
Transcriptional Regulation of Endothelial Cells after Neonatal Lung InjuryR01HL141174 · NHLBI · UNIVERSITY OF ARIZONA · PI Vladimir Kalinichenko · 2018 to 2026
$4.7M
LungMap Phase II - Building a multidimensional map of developing human lungU01HL148856 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI WHITSETT, JEFFREY A, XU, YAN · 2019 to 2023
$4.5M
Development of novel therapeutic approaches for treatment of Alveolar Capillary DysplasiaR01HL152973 · NHLBI · UNIVERSITY OF ARIZONA · PI Vladimir Kalinichenko · 2021 to 2026
$3.6M
Epigenomic dysfunction at 16q24.1 vascular defects and perinatal consequencesR01HL137203 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI STANKIEWICZ, PAWEL · 2017 to 2020
$2.0M
Transcriptional regulation of goblet cell metaplasiaR01HL123490 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI KALINICHENKO, VLADIMIR · 2014 to 2017
$1.6M
Targeting Foxm1 in pulmonary fibrosisR01HL132849 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI KALIN, TANYA · 2016 to 2019
$1.5M
NHLBI NIH HHS R01 HL084151NHLBI NIH HHS R01 HL123490NHLBI NIH HHS R01 HL132849NHLBI NIH HHS R01 HL137203NHLBI NIH HHS R01 HL141174NHLBI NIH HHS R01 HL152973NHLBI NIH HHS U01 HL148856
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression RegulationMutationAnimalsForkhead Transcription FactorsHumansMiceModels, AnimalPersistent Fetal Circulation SyndromePulmonary AlveoliSignal TransductionForkhead Transcription FactorsFOXF1 protein, humanFoxf1 protein, mouseACDMPValveolar capillary dysplasia with misalignment of pulmonary veinsFOXF1 transcription factorneonatal pulmonary angiogenesisSTAT3

Identifiers

PMID31199666
PMCPMC6794119
OpenAlexW2950406303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.