Evidence map›Paper›PMID 31199542›Full record

ArticleJournal of leukocyte biology2019

Frontline Science: Late CD27 stimulation promotes IL-7Rα transcriptional re-expression and memory T cell qualities in effector CD8

Han Dong, Andrew Buckner, Jessica Prince, Timothy Bullock

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of leukocyte biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Han DongDepartment of Pathology and Human Immune Therapy Center, University of Virginia, Charlottesville, Virginia, 22908, USA.
Andrew BucknerDepartment of Pathology and Human Immune Therapy Center, University of Virginia, Charlottesville, Virginia, 22908, USA.
Jessica PrinceDepartment of Pathology and Human Immune Therapy Center, University of Virginia, Charlottesville, Virginia, 22908, USA.
Timothy BullockDepartment of Pathology and Human Immune Therapy Center, University of Virginia, Charlottesville, Virginia, 22908, USA.
University of Virginia · US

Funding

CD70 mediated costimulation of T cell responsesR01CA115882 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI BULLOCK, TIMOTHY N. · 2005 to 2007
$722k
NCI NIH HHS R01 CA115882
6 · The paper itself

Abstract

We previously demonstrated that CD27 co-stimulation during a primary CD8

Indexed as

Immunologic MemoryAnimalsCD8-Positive T-LymphocytesCell DifferentiationMiceMice, KnockoutReceptors, Antigen, T-CellReceptors, Interleukin-7Signal TransductionSTAT5 Transcription FactorTumor Necrosis Factor Receptor Superfamily, Member 7interleukin-7 receptor, alpha chainReceptors, Antigen, T-CellReceptors, Interleukin-7STAT5 Transcription FactorTumor Necrosis Factor Receptor Superfamily, Member 7CD27costimulationIL7memory

Identifiers

PMID31199542
PMCPMC6824422
OpenAlexW2952174619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.