Evidence map›Paper›PMID 31199068›Full record

ArticleMicrobial biotechnology2019

Pseudomonas putida KT2440 is HV1 certified, not GRAS.

Linde F C Kampers, Rita J M Volkers, Vitor A P Martins Dos Santos

Abstract readLetter
In one paragraph

Article in Microbial biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Review
  3. Beyond the Usual Suspects: EmergingInternational journal of molecular sciences · 2026
    Review
  4. Article
  5. Article
  6. EngineeringACS synthetic biology · 2026
    Article
  7. Multi-strain analysis ofmSystems · 2026
    Article
  8. Unique metabolic traits ofJournal of bacteriology · 2026
    Review
  9. Multi-strain Analysis ofbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Journal of bacteriology · 2024
    Review
  17. Genetic Code Expansion in Pseudomonas putida KT2440.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Linde F C KampersLaboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Stippeneng 4, 6708, Wageningen, The Netherlands.ORCID 0000-0002-3479-3593
Rita J M VolkersLaboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Stippeneng 4, 6708, Wageningen, The Netherlands.
Vitor A P Martins Dos SantosLaboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Stippeneng 4, 6708, Wageningen, The Netherlands.ORCID 0000-0002-2352-9017

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas putida is rapidly becoming a workhorse for industrial production due to its metabolic versatility, genetic accessibility and stress-resistance properties. The P. putida strain KT2440 is often described as Generally Regarded as Safe, or GRAS, indicating the strain is safe to use as food additive. This description is incorrect. P. putida KT2440 is classified by the FDA as HV1 certified, indicating it is safe to use in a P1 or ML1 environment.

Indexed as

Food MicrobiologyFood SafetyIndustrial MicrobiologyPseudomonas putidaUnited StatesUnited States Food and Drug Administration

Identifiers

PMID31199068
PMCPMC6680625

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.