Evidence map›Paper›PMID 31198832›Full record

ArticleData in brief2019

Data on peptidyl platform-based anticancer drug synthesis and triton-x-based micellar clusters (MCs) self-assembly peculiarities for enhanced solubilization, encapsulation of hydrophobic compounds and their interaction with HeLa cells.

Alexey V Solomonov, Yuriy S Marfin, Evgeniy V Rumyantsev, Elena Ragozin, Talia Shekhter Zahavi, Gary Gellerman, Alexander B Tesler, Falk Muench, Akiko Kumagai, Atsushi Miyawaki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Alexey V SolomonovInorganic Chemistry Department, Ivanovo State University of Chemistry and Technology, 7 Sheremetevskij prosp., 153000, Ivanovo, Russian.
Yuriy S MarfinInorganic Chemistry Department, Ivanovo State University of Chemistry and Technology, 7 Sheremetevskij prosp., 153000, Ivanovo, Russian.
Evgeniy V RumyantsevInorganic Chemistry Department, Ivanovo State University of Chemistry and Technology, 7 Sheremetevskij prosp., 153000, Ivanovo, Russian.
Elena RagozinDepartment of Chemical Sciences, Ariel University of Samaria, Ariel, Israel.
Talia Shekhter ZahaviDepartment of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 69978, Israel.
Gary GellermanDepartment of Chemical Sciences, Ariel University of Samaria, Ariel, Israel.
Alexander B TeslerDepartment of Materials and Interfaces, Faculty of Chemistry, Weizmann Institute of Science, 76100, 234 Herzl Street, Rehovot, Israel.
Falk MuenchDepartment of Materials and Earth Sciences, Technische Universität Darmstadt, Alarich-Weiss-Strasse 2, 64287, Darmstadt, Germany.
Akiko KumagaiCentre of Brain Science, Laboratory for Cell Function and Dynamics, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
Atsushi MiyawakiCentre of Brain Science, Laboratory for Cell Function and Dynamics, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
Ariel University · ILIvanovo State University of Chemistry and Technology · RURIKEN Center for Brain Science · JPIvanovo State Polytechnic University · RUTechnical University of Darmstadt · DETel Aviv University · ILWeizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The data presented here refer to a research article entitled "Self-Assembled Micellar Clusters Based on Triton-X-family Surfactants for Enhanced Solubilization, Encapsulation, Proteins Permeability Control, and Anticancer Drug Delivery" Solomonov et al., 2019. The present article provides the General Procedure for clusterization of Triton-X-based micelles and the effect of (i) metal ion, surfactant, and chelator concentration on the developed clusters formation, (ii) surfactant-chelator relation change, (iii) metal ion-micelles concertation ratio variation, (iv) metal ion replacement, (v) solvent replacement, (vi) kinetics of clusters formation, (vii) hydrophobic fluorescent dye (Coumarin 6) solubilization in aqueous MCs media, (viii) novel anticancer peptidyl drug synthesis and characterization and (ix) the viability of HeLa cells with and without the presence of drug-free Triton-X-based family MCs. These data provide additional insights useful for understanding all aspects of the micellar clusters formation, optimization, and control.

Indexed as

Anticancer drug synthesisEncapsulationFluorescence enhancementMicellar clustersSelf-assemblySurfactantsTriton-X

Identifiers

PMID31198832
PMCPMC6556622
OpenAlexW2946339554

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.