Evidence map›Paper›PMID 31198741›Full record

ArticleJournal of family medicine and primary care2019

Serum vitamin D level, sun-exposed area, dietary factors, and physical activity as predictors of invasive breast cancer risk among Sudanese women: A case-control study.

Nazik Elmalaika Husain, Ahmed A Suliman, Ismail Abdelrahman, Shahinaz A Bedri, Rasha M Musa, Hind E Osman, Ayda H Mustafa, Nahla Gafer, Ehab Farah, Ali Abdel Satir and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Sun Exposure Is Associated with Reduced Breast Cancer Risk among Women Living in the Caribbean: The Atabey Study in Puerto Rico.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 4 countries.

Nazik Elmalaika HusainDepartment of Pathology, Omdurman Islamic University, Omdurman, Sudan.
Ahmed A SulimanDepartment of Pathology, National Ribat University, Sudan.
Ismail AbdelrahmanDepartment of Pathology, National Ribat University, Sudan.
Shahinaz A BedriDepartment of Pathology, Faculty of Medicine, Ahfad University for Women, Omdurman, Sudan.
Rasha M MusaDepartment of Medical Laboratories, National Ribat University Hospital, Sudan.
Hind E OsmanDepartment of Pathology, Faculty of Veterinary Medicine, Sudan University for Science and Technology, Sudan.
Ayda H MustafaBreast Combined Clinic, RICK and Department of Surgery, Alneelain University, Sudan.
Nahla GaferOncology and Palliative Care Unit, Radiation and Isotope Center, Khartoum, Sudan.
Ehab FarahDepartment of Statistics, Faculty of Sciences, University of Tabouk, Saudi Arabia.
Ali Abdel SatirHisto-center, Khartoum, Sudan.
Mohamed H AhmedDepartment of Medicine and HIV Metabolic Clinic, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes, Buckinghamshire, UK.
Mugtaba OsmanArmed Forces Centre for Psychiatric Care, Taif, Saudi Arabia.
Abbas AgaimyInstitute of Pathology, University of Erlangen, Erlangen, Germany.
National Ribat University · SDAhfad University for Women · SDAl-Neelain University · SDArmed Forces Hospital · SAFriedrich-Alexander-Universität Erlangen-Nürnberg · DEMilton Keynes Hospital · GBOmdurman Islamic University · SDSudan University of Science and Technology · SDUniversity of Tabuk · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of vitamin D in the development, progression, and prognosis of breast cancer, though widely studied worldwide, has been inconclusive. This study intended to assess the role of some factors (including serum vitamin D level, sun-exposed area, dietary factors, and physical activity) as predictors of the development of invasive breast cancer (IBC) among Sudanese women.

methodsA case-control study was conducted on 200 Sudanese women (100 with newly diagnosed IBC and 100 matched healthy females). Serum 25-hydroxyvitamin D was measured through a competitive electrochemiluminescence immunoassay. Matching analysis was adopted by R version 3.4.1 making use of the "MatchIt" package for calculating propensity scores to build a confounder-adjusted, multiple generalized, linear logistic regression model.

resultsParticipants' age ranged from 28 to 85 years with a mean [±standard deviation (SD)] of 48.10 (±12.11) years. The mean (±SD) serum vitamin D level was 12.97 (±8.60) and 13.79 (±6.79) ng/mL in breast cancer and noncancer Sudanese women, respectively [P = 0.013; odds ratio (OR) 0.862; 95% confidence interval (CI) 0.766-0.969; β = 0.149)]. Sun-exposed area (

conclusionThe higher the plasma vitamin D level by one unit, the lower the risk of breast cancer by 13.84%. Sedentary lifestyle, reduced sun-exposed skin area, and low serum vitamin D levels can be considered as predictors of IBC. Encouraging moderate physical activity and consumption of certain foods may, in part, decrease the precipitating risks of breast cancer. More studies and research are needed to confirm these findings.

Indexed as

Breast cancerdietphysical activityrisk factorsSudansun-exposed areavitamin D

Identifiers

PMID31198741
PMCPMC6559091
OpenAlexW2948948557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.