Evidence map›Paper›PMID 31198672›Full record

ArticleTaiwan journal of ophthalmology

Bilateral cytomegalovirus retinitis comorbid with diabetic macular edema.

Yu-Jang Chao, Yi-Ming Huang, Yu-Chien Chung, De-Kuang Hwang, Shih-Jen Chen, Catherine Jui-Ling Liu

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu-Jang ChaoDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
Yi-Ming HuangDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
Yu-Chien ChungDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
De-Kuang HwangDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
Shih-Jen ChenDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
Catherine Jui-Ling LiuDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
Taipei Veterans General Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) retinitis comorbid with diabetic retinopathy is uncommon. We report a case of bilateral CMV retinitis and diabetic retinopathy in a patient who underwent pancreas transplantation and share the experience of the treatment outcome. An 18-year-old male diagnosed with type-1 diabetes mellitus received pancreas transplantation and immunosuppressive therapy suffered from progressively blurred vision in both eyes for several days. His visual acuity was 20/100 in the right eye and 20/50 in the left eye. Ophthalmic examination revealed bilateral diabetic macular edema (DME) without intraocular inflammatory signs in either eye. The DME subsided after 2 monthly intravitreal injections of aflibercept. However, bilateral panuveitis with CMV retinitis was observed after antivascular endothelial growth factor therapy. The retinitis subsided gradually but completely after systemic and intravitreal antiviral therapy. However, bilateral DME recurred and persisted despite repeated injections of aflibercept during the resting follow-up period. Our case suggests that CMV retinitis can coexist with other retinal diseases, including diabetic retinopathy. Treatment is difficult in such cases.

Indexed as

Cytomegaloviruscytomegalovirus retinitisdiabetic macular edemadiabetic retinopathypancreas transplantation

Identifiers

PMID31198672
PMCPMC6557065
OpenAlexW2803357828

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.