Evidence map›Paper›PMID 31198626›Full record

ArticlePeerJ2019

Identification and characterization of mRNAs and lncRNAs in the uterus of polytocous and monotocous Small Tail Han sheep (

Yongfu La, Jishun Tang, Xiaoyun He, Ran Di, Xiangyu Wang, Qiuyue Liu, Liping Zhang, Xiaosheng Zhang, Jinlong Zhang, Wenping Hu and 1 more

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  3. Long non-coding RNAFrontiers in veterinary science · 2024
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  9. Article
  10. lncRNAMolecular therapy. Nucleic acids · 2021
    Article
  11. Article
  12. Article
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  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yongfu La *Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Genetics and Breeding and Reproduction of Ministry of Agriculture, Institute of Animal Science, Beijing, China.
Jishun Tang *Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Genetics and Breeding and Reproduction of Ministry of Agriculture, Institute of Animal Science, Beijing, China.
Xiaoyun HeChinese Academy of Agricultural Sciences, Key Laboratory of Animal Genetics and Breeding and Reproduction of Ministry of Agriculture, Institute of Animal Science, Beijing, China.
Ran DiChinese Academy of Agricultural Sciences, Key Laboratory of Animal Genetics and Breeding and Reproduction of Ministry of Agriculture, Institute of Animal Science, Beijing, China.
Xiangyu WangChinese Academy of Agricultural Sciences, Key Laboratory of Animal Genetics and Breeding and Reproduction of Ministry of Agriculture, Institute of Animal Science, Beijing, China.
Qiuyue LiuChinese Academy of Agricultural Sciences, Key Laboratory of Animal Genetics and Breeding and Reproduction of Ministry of Agriculture, Institute of Animal Science, Beijing, China.
Liping ZhangGansu Agricultural University, College of Animal Science and Technology, Lanzhou, China.
Xiaosheng ZhangTianjin Institute of Animal Sciences, Tianjin, China.
Jinlong ZhangTianjin Institute of Animal Sciences, Tianjin, China.
Wenping HuChinese Academy of Agricultural Sciences, Key Laboratory of Animal Genetics and Breeding and Reproduction of Ministry of Agriculture, Institute of Animal Science, Beijing, China.
Mingxing ChuChinese Academy of Agricultural Sciences, Key Laboratory of Animal Genetics and Breeding and Reproduction of Ministry of Agriculture, Institute of Animal Science, Beijing, China.
Chinese Academy of Agricultural Sciences · CNGansu Agricultural University · CNInstitute of Animal Sciences · CNTianjin Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong non-coding RNAs (lncRNAs) regulate endometrial secretion and uterine volume. However, there is little research on the role of lncRNAs in the uterus of Small Tail Han sheep (

methodsTo identify lncRNA and mRNA expressed in the uterus, the expression of lncRNA and mRNA in the uterus of Small Tail Han sheep (

resultsIn the follicular phase, 473 lncRNAs and 166 mRNAs were differentially expressed in polytocous and monotocous sheep; in the luteal phase, 967 lncRNAs and 505 mRNAs were differentially expressed in polytocous and monotocous sheep. GO and KEGG enrichment analysis showed that the differentially expressed lncRNAs and their target genes are mainly involved in ovarian steroidogenesis, retinol metabolism, the oxytocin signaling pathway, steroid hormone biosynthesis, and the Foxo signaling pathway. Key lncRNAs may regulate reproduction by regulating genes involved in these signaling pathways and biological processes. Specifically,

Indexed as

LncRNAsProlificacyRNA-SeqSmall Tail Han sheepUterus

Identifiers

PMID31198626
PMCPMC6535221
OpenAlexW2946035727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.